Dynamic hypoxic pre-conditioning of cells seeded in tissue-engineered scaffold to improve neovascularisation

JOY Ho - 2023 - discovery.ucl.ac.uk
Mesenchymal stem cells (MSC) have the most … 3D hydrogel to enhance MSC angiogenic
pathway using real-time continuous oxygen sensors and angiogenic cytokine profiling. Cell

[HTML][HTML] Enhancement strategies for mesenchymal stem cells and related therapies

S Alagesan, J Brady, D Byrnes, J Fandiño… - Stem Cell Research & …, 2022 - Springer
… This has been exploited for use in MSC-mediated delivery of … Hypoxia used as a pre-conditioning
tool has been shown to … and in vivo after subcutaneous injection on an H460 xenograft …

Mesenchymal Stromal Cells (MSCs): a promising tool for cell-based angiogenic therapy

C Ulpiano, CL da Silva, GA Monteiro - Current Gene Therapy, 2021 - ingentaconnect.com
… , including ex vivo preconditioning and genetic modification … exploited bioengineering
approaches, such as ex vivo cell … were delivered to the lesioned areas in the brain by injection

[HTML][HTML] Injectable hydrogel-based nanocomposites for cardiovascular diseases

X Liao, X Yang, H Deng, Y Hao, L Mao… - … in Bioengineering and …, 2020 - frontiersin.org
… have been developed with matrix metalloproteinase (MMP) to create an assistive
microenvironment for delivery of bone marrow-derived mesenchymal stem cells (BMSCs) into the …

Bioinspired short peptide hydrogel for versatile encapsulation and controlled release of growth factor therapeutics

SH Hiew, JK Wang, K Koh, H Yang, A Bacha, J Lin… - Acta Biomaterialia, 2021 - Elsevier
hydrogels loaded with adipose-derived mesenchymal stem … be exploited as an encapsulant
material for secretome delivery… h preconditioning for human embryonic stem cells secretome …

Engineering an Injectable hMSC-Exosome-Laden Hydrogel for Biologically Active Annulus Fibrosus Repair

TJ DiStefano - 2021 - search.proquest.com
… was to develop an injectable hydrogel system with pro-… delivery of mesenchymal stem cell
(MSC)-derived exosomes to promote biologically active AF repair. Results showed that AF cell

[HTML][HTML] Mesenchymal stem cells in burn wound management

A Surowiecka, A Chrapusta… - International Journal of …, 2022 - mdpi.com
… form of stem cell application were intradermal injections in … Hydrogel and ADSCs in
combination were used in full-thickness … Curcumin-preconditioned ADSCs may show potential in …

[HTML][HTML] Recent advances on drug-loaded mesenchymal stem cells with anti-neoplastic agents for targeted treatment of cancer

A Babajani, P Soltani, E Jamshidi, MH Farjoo… - … in bioengineering and …, 2020 - frontiersin.org
stem cells as both a therapeutic agent and a drug delivery vehicle. Among different types of
stem cells, mesenchymal stem cells (… methods for delivery is systemic injection of MSCs in …

[HTML][HTML] Alkaline activation of endogenous latent TGFβ1 by an injectable hydrogel directs cell homing for in situ complex tissue regeneration

S Wang, Y Niu, P Jia, Z Liao, W Guo, RC Chaves… - Bioactive Materials, 2022 - Elsevier
… marrow stem cells (hBMSCs). On this basis, we engineered an … (ECM), thereby promoting
mesenchymal stem cell (MSCs) … done at 5% strain/min after preconditioning for 10 cycles (1–5…

Therapeutic applications of mesenchymal stem cells:: a comprehensive review

P Samadi, S Saki, H Manoochehri… - Current Stem Cell …, 2021 - ingentaconnect.com
… /gelatin hydrogel with TGF-β3-loaded nanoparticles are co-delivered … ing results with these
cells, clinical trials can exploit MSCs in … evidence that IV or IP injection of MSCs from different …