… mucins in the airways. In addition, MUC2 and MUC19 are also part of airway mucus, albeit
to a … innate and adaptive immune functions against all types of harmful intruders entering the …

… > 40 nm into the layer, and its barrier properties become even more impressive near the cell
surface… In addition to molecular barrier features, cell surface mucins have substantial roles in …

… In the intrapulmonary airways, a non-adherent layer of mucus is secreted from surface … the
unique barrier properties of the airway epithelium, and the properties and mechanisms of its …

… of inhaled particles trapped in mucus. As it relies on both mucus viscosity and ciliary function…
Besides its physical barrier and innate immune functions, the AE is able to sense alterations …

… most obvious clinical symptoms are related to airway mucus, its excessive production,
and an inability to clear it. MCC is a vital feature of the innate immune system in the airways [6,7]. …

… , it results in ineffective airway clearance with mucus plugging, airway obstruction, and … of
airway epithelial cells is their innate ability to recognize danger at the respiratory barrier. This is …

… In the case of asthma, however, the increased mucin content of the airway mucus attracts …
-associated macrophages), they are the most frequent cell type carrying our innate immune …

… sputum produced. Despite these considerations, sputum is widely used to study airway mucus
and airway … are a first line of innate immunity, being secreted by airway epithelial cells and …

… remains largely phenomenological and an understanding of mechanisms that allow the
transport of airway mucus remain limited. Mucus is separated from the airway’s epithelial surface …

… composition of the mucus layer, mucus barrier properties, different mucus models and drug
… on mucus properties. Furthermore, there are animal models with abnormal mucus barrier, …