[HTML][HTML] Metabolism and innate immunity meet at the mitochondria

A Bahat, T MacVicar, T Langer - Frontiers in Cell and Developmental …, 2021 - frontiersin.org
… immune signalling and how mtDNA release and innate immunity are coupled to metabolism
integrate metabolic regulation within effective innate immune responses to viral infection. We …

[HTML][HTML] Virus infections and host metabolism—can we manage the interactions?

D Sumbria, E Berber, M Mathayan… - Frontiers in …, 2021 - frontiersin.org
… In addition, innate responses set off by viral infections, such as interferons type I and II, also
metabolic events that occur during viral infections. We advocate that manipulating metabolic

[HTML][HTML] Metabolic host response and therapeutic approaches to influenza infection

M Keshavarz, F Solaymani-Mohammadi… - Cellular & Molecular …, 2020 - Springer
viral infection affects cell function via alteration in amino acid synthesis, membrane composition,
and lipid metabolism. … Innate immune cells can recognize influenza A viruses and their …

[HTML][HTML] Innate immune responses to acute viral infection during pregnancy

EF Cornish, I Filipovic, F Åsenius, DJ Williams… - Frontiers in …, 2020 - frontiersin.org
innate immune correlates of the increased severity of influenza in pregnancy, much less is
known about the other viruses … , and timing of innate immune responses to viral infection in …

Immunometabolism of infections

JS Ayres - Nature Reviews Immunology, 2020 - nature.com
metabolic regulation of the antiviral immune response. Upon viral infection of a cell, cytosolic
viral … with the induction of innate immune and pathogen response genes. Consistent with …

[HTML][HTML] Metabolic requirements of NK cells during the acute response against retroviral infection

E Littwitz-Salomon, D Moreira, JN Frost, C Choi… - Nature …, 2021 - nature.com
… This metabolic response involves the upregulation of nutrient … mitochondrial machinery
after acute virus infection. The antiviral … As part of the innate immune system, NK cells respond

[HTML][HTML] Viruses and metabolism: the effects of viral infections and viral insulins on host metabolism

K Girdhar, A Powis, A Raisingani… - Annual review of …, 2021 - annualreviews.org
… cross-talk between viruses and host metabolism. Several studies have … viral infections
manipulate metabolic pathways including glucose, fatty acid, protein, and nucleotide metabolism. …

[HTML][HTML] Amino acid metabolism and signalling pathways: potential targets in the control of infection and immunity

D Tomé - Nutrition & Diabetes, 2021 - nature.com
innate inflammatory immune response to viral infections [19]. In this initial phase of the
innate immune responses … -expressing macrophages dominate in response to pro-inflammatory …

[HTML][HTML] Hepatitis B virus rigs the cellular metabolome to avoid innate immune recognition

L Zhou, R He, P Fang, M Li, H Yu, Q Wang, Y Yu… - Nature …, 2021 - nature.com
… To investigate global metabolic changes during HBV infection, … with oncogenic viruses
such as Epstein–Barr virus, human … that HBV infections—and maybe other viral infections–…

[HTML][HTML] Role of metabolic reprogramming in pulmonary innate immunity and its impact on lung diseases

C Michaeloudes, PK Bhavsar, S Mumby, B Xu… - Journal of Innate …, 2020 - karger.com
… The main types of viruses causing airway disease, human … virus and influenza A virus
are recognised by the innate immune system through PRRs. During viral infection, the viral