[HTML][HTML] Integrated analysis of single-cell RNA-seq and bulk RNA-seq unravels tumour heterogeneity plus M2-like tumour-associated macrophage infiltration and …

X Bao, R Shi, T Zhao, Y Wang, N Anastasov… - Cancer Immunology …, 2021 - Springer
… detailed bioinformatics analyses of individual tumour cells, bulk RNA-seq data and clinical
data, we describe the tumour heterogeneity in TNBC and the association of M2-like tumour-…

[HTML][HTML] Integration of single-cell sequencing and bulk RNA-seq to identify and develop a prognostic signature related to colorectal cancer stem cells

J Wu, W Li, J Su, J Zheng, Y Liang, J Lin, B Xu… - Scientific Reports, 2024 - nature.com
… The pronounced heterogeneity of CRC cells coupled with … the integration of scRNA-seq and
Bulk RNA-seq analysis. The … avenues aimed at unraveling the molecular underpinnings of …

Integrated analysis of single-cell RNA-seq and bulk RNA-seq unravels T cell-related prognostic risk model and tumor immune microenvironment modulation in triple …

S Guo, X Liu, J Zhang, Z Huang, P Ye, J Shi… - Computers in biology …, 2023 - Elsevier
… In conclusion, this study focused on exploring the T cell profile and TME of … and bulk RNA-seq
and revealed key potential prognostic genes. This study first elucidated the heterogeneity

[HTML][HTML] Integrated single-cell and bulk RNA-Seq analysis enhances prognostic accuracy of PD-1/PD-L1 immunotherapy response in lung adenocarcinoma through …

P Sui, X Liu, C Zhong, Z Sha - Scientific Reports, 2024 - nature.com
… , our study initially focuses on unraveling the intricate … significant heterogeneity among
CAFs in various cancer contexts… Through our comprehensive analysis between the necroptotic …

[HTML][HTML] Integration of bulk RNA sequencing data and single-cell RNA sequencing analysis on the heterogeneity in patients with colorectal cancer

J Zhang, Y Wu, Z Shen - Functional & Integrative Genomics, 2023 - Springer
… of tumorigenesis including colorectal cancer. This work … cancer using Bulk RNA-seq and
single-cell RNA-seq (scRNA… RNA-seq unravels tumour heterogeneity plus M2-like tumour-…

Integrated analysis of single-cell RNA-seq and bulk RNA-seq to unravel the molecular mechanisms underlying the immune microenvironment in the development of …

Y Su, X Zhang, Y Liang, J Sun, C Lu… - Biochimica et Biophysica …, 2024 - Elsevier
… Regarding prognostic analysis, IGLC3, IGLV1–44, IGKV1–16, … analysis of the IGC single-cell
atlas together with bulk transcriptome data contributes to understanding TME heterogeneity

[HTML][HTML] Integrated analysis of single-cell RNA-seq and bulk RNA-seq unravels the heterogeneity of cancer-associated fibroblasts in TNBC

X Wu, W Lu, W Zhang, D Zhang, H Mei, M Zhang… - Aging (Albany …, 2023 - ncbi.nlm.nih.gov
… in TNBC are heterogeneous and that this heterogeneity may … In the present study, to explore
the heterogeneity of CAFs in … -seq and bulk RNA-seq, described the tumor heterogeneity in …

[HTML][HTML] Integrated analysis of single-cell and bulk RNA-sequencing reveals tumor heterogeneity and a signature based on NK cell marker genes for predicting …

S Li, H Du, D Gan, X Li, X Zao, Y Ye - Frontiers in Pharmacology, 2023 - frontiersin.org
… In this study, we identified distinct genetic subtypes in order to unravel the tumor heterogeneity
of HCC. Moreover, … Identification of NK cell marker genes by single cell RNA-seq analysis

[HTML][HTML] Single-cell and Bulk RNA-Seq reveal angiogenic heterogeneity and microenvironmental features to evaluate prognosis and therapeutic response in lung …

L Tang, Z Chen, J Yang, Q Li, S Wang, T Mo… - Frontiers in …, 2024 - frontiersin.org
… Methods: We employed integrated single-cell and bulk transcriptome sequencing to
unravel the heterogeneity of … Tumor heterogeneity is the main cause of drug resistance and …

[PDF][PDF] … interactions between tumor-associated macrophages and consensus molecular subtypes in colorectal cancer: An integrative analysis of single-cell and bulk …

H Gao, L Ma, Q Zou, B Hu, K Cai, Y Sun, L Lu, D Ren - Heliyon, 2023 - cell.com
… the complex 100 biological heterogeneity of TAMs in TME and … bulk RNA-seq data to explore
the tumor 103 heterogeneity in … Vermeulen, From tumour heterogeneity to advances 555 in …