[HTML][HTML] Integrative analysis of single-cell and bulk RNA sequencing unveils the senescence landscape in ischemic stroke

L Fu, B Yu, Y Zhang, S Cao, B Lv, Y Tian… - Aging (Albany …, 2023 - ncbi.nlm.nih.gov
L Fu, B Yu, Y Zhang, S Cao, B Lv, Y Tian, H Chen, S Yang, Y Hu, J Hua, P Ren, J Li, S Gong
Aging (Albany NY), 2023ncbi.nlm.nih.gov
Ischemic stroke (IS) is a fatal neurological disease that occurs when the blood flow to the
brain is disrupted, leading to brain tissue damage and functional impairment. Cellular
senescence, a vital characteristic of aging, is associated with a poor prognosis for IS. This
study explores the potential role of cellular senescence in the pathological process following
IS by analyzing transcriptome data from multiple datasets (GSE163654
Abstract
Ischemic stroke (IS) is a fatal neurological disease that occurs when the blood flow to the brain is disrupted, leading to brain tissue damage and functional impairment. Cellular senescence, a vital characteristic of aging, is associated with a poor prognosis for IS. This study explores the potential role of cellular senescence in the pathological process following IS by analyzing transcriptome data from multiple datasets (GSE163654
ncbi.nlm.nih.gov
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