Interaction between iron oxide nanoparticles (Fe3O4 NPs) and human neutrophils: Evidence that Fe3O4 NPs possess some pro-inflammatory activities

A Saafane, D Girard - Chemico-Biological Interactions, 2022 - Elsevier
… superparamagnetic iron oxide NPs (Ferumoxtran-10) were found to be ingested by human
monocyte-macrophages in vitro [40]. Intriguingly, it was reported that, in vivo, iron oxide NPs …

In vitro cytotoxicity study of superparamagnetic iron oxide and silica nanoparticles on pneumocyte organelles

A Solorio-Rodríguez, V Escamilla-Rivera… - Toxicology in Vitro, 2021 - Elsevier
… It is important to emphasize that we observed the interaction of NP-loaded vesicles and … In
agreement with our findings, in vivo studies have shown that SiO 2 NP are particularly capable …

Delivery of magnetic nanoparticles to lung cancer cells via polarized macrophages: A riveting tale of a bio-inspired phenomenon

VV Agnihotri, AP Gorle - Medical Hypotheses, 2023 - Elsevier
… of iron and macrophages, in-vitro internalization of iron … At the beginning of tumorigenesis,
alveolar macrophages (AMs) are … interaction of iron and macrophages, the potential of in-vitro

[HTML][HTML] The use of iron oxide nanoparticles to reprogram macrophage responses and the immunological tumor microenvironment

V Mulens-Arias, JM Rojas, DF Barber - Frontiers in immunology, 2021 - frontiersin.org
… different cell types, especially their interaction with the macrophages that are involved in their
… and macrophage activation, and to reduce the OVA-expressing CT26 tumor burden in vivo (…

[HTML][HTML] Biological interactions of ferromagnetic iron oxide–carbon nanohybrids with alveolar epithelial cells

S Vercellino, I Kokalari, ML Cantoral, V Petseva… - Biomaterials …, 2022 - pubs.rsc.org
Iron oxide nanoparticles (IONPs) have been largely … @C biological interactions in vitro,
providing them with an in vivo-… a widely employed model of alveolar epithelial cells for a variety of …

The intrinsic biological identities of iron oxide nanoparticles and their coatings: Unexplored territory for combinatorial therapies

V Mulens-Arias, JM Rojas, DF Barber - Nanomaterials, 2020 - mdpi.com
… Over the last 20 years, iron oxide nanoparticles (IONPs) have … the complex dynamics of
their interaction with biological systems (… , IONPs also interact with different cell types in vivo, a …

Understanding the influence of experimental factors on bio-interactions of nanoparticles: towards improving correlation between in vitro and in vivo studies

P Natarajan, JM Tomich - Archives of Biochemistry and Biophysics, 2020 - Elsevier
… of NPs influence their bio-interactions to a large extent. This review discusses recent
studies that help understand the nano-bio interactions of iron oxide and gold NPs with different …

p53 Promotes Ferroptosis in Macrophages Treated with Fe3O4 Nanoparticles

C Wu, Z Shen, Y Lu, F Sun, H Shi - ACS Applied Materials & …, 2022 - ACS Publications
… in vivo, but their cytotoxicity in vivo is not yet apparent. As most of the NPs applied in vivo are
captured and metabolized by macrophages… basis for studying the cytotoxicity of NPs in vivo. …

[HTML][HTML] Modulation of Pulmonary Toxicity in Metabolic Syndrome Due to Variations in Iron Oxide Nanoparticle-Biocorona Composition

L Xia, S Alqahtani, CR Ferreira, UK Aryal, K Biggs… - Nanomaterials, 2022 - mdpi.com
… and inflammatory responses were evaluated in vitro to determine the contribution of …
within alveolar macrophages demonstrating that they are a primary cell type interacting with …

Influence of polymer shell molecular weight on functionalized iron oxide nanoparticles morphology and in vivo biodistribution

RC Popescu, BŞ Vasile, DI Savu, GD Mogoşanu… - Pharmaceutics, 2022 - mdpi.com
… terms of in vivo behavior [27,28,29,30] However, the mechanisms of interaction between the
… in the liver inside the Kupffer cells and in alveolar macrophages in the lungs, which was in …