Use of a human small airway epithelial cell line to study the interactions of Aspergillus fumigatus with pulmonary epithelial cells

H Liu, J Lin, QT Phan, FN Gravelat, DC Sheppard… - Msphere, 2023 - Am Soc Microbiol
… of invasive aspergillosis, Aspergillus fumigatus interacts with the epithelial cells that line the
… and vascular endothelial cells (38). Whether these proteins can also function as bridging …

Aspergillus fumigatus—Host Interactions Mediating Airway Wall Remodelling in Asthma

S Namvar, B Labram, J Rowley, S Herrick - Journal of Fungi, 2022 - mdpi.com
Vascular leakiness is a key pathophysiological feature of asthma that correlates with induction
of Vascular Endothelial Growth Factor (VEGF) and occurs in advance of inflammation in …

[HTML][HTML] Bronchial epithelial cells on the front line to fight lung infection-causing Aspergillus fumigatus

J Bigot, L Guillot, J Guitard, M Ruffin, H Corvol… - Frontiers in …, 2020 - frontiersin.org
… Schematically, the interaction between Aspergillus fumigatus and the BECs leads to three …
Summary of the interactions between bronchial epithelial cells and Aspergillus fumigatus. For …

Novel host pathways govern epithelial cell invasion of Aspergillus fumigatus

H Liu, AC Shetty, AS Ibrahim, SG Filler… - Microbiology …, 2023 - Am Soc Microbiol
… conidia swell and then germinate to form hyphae that invade the epithelial cell lining of the
airways. Because pulmonary epithelial cells are one of the first host cells to interact with A. …

Bacterial Interactions with Aspergillus fumigatus in the Immunocompromised Lung

A Margalit, JC Carolan, K Kavanagh - Microorganisms, 2021 - mdpi.com
… pulmonary infections, are those arising from the interactions between Aspergillus fumigatus
and P. aeruginosa. Aspergillus fumigatus is the most common fungal pathogen isolated from …

Novel Insights into Aspergillus fumigatus Pathogenesis and Host Response from State-of-the-Art Imaging of Host–Pathogen Interactions during Infection

SC Ortiz, K Pennington, DD Thomson, M Bertuzzi - Journal of Fungi, 2022 - mdpi.com
epithelial cellsepithelial cells cannot be excluded. Additionally, this study focused solely
on identifying in vivo uptake by bronchial epithelial cells, and uptake by alveolar epithelial cells

Aspergillus fumigatus cell wall promotes apical airway epithelial recruitment of human neutrophils

MB Feldman, RA Dutko, MA Wood, RA Ward… - Infection and …, 2020 - Am Soc Microbiol
… inflammation, as signaled by neutrophil recruitment and transmigration to the airspaces
where neutrophils can interact with conidia in the first hours following infection. In the present …

Differential Proinflammatory Responses to Aspergillus fumigatus by Airway Epithelial Cells In Vitro Are Protease Dependent

J Rowley, S Namvar, S Gago, B Labram, P Bowyer… - Journal of Fungi, 2021 - mdpi.com
… Both direct fungal cell wall–epithelial cell interaction and secretion of soluble proteases
have been proposed as possible mechanisms. Our aim was to determine the contribution of …

[HTML][HTML] Invasive aspergillosis-on-chip: A quantitative treatment study of human Aspergillus fumigatus infection

TNM Hoang, Z Cseresnyés, S Hartung, M Blickensdorf… - Biomaterials, 2022 - Elsevier
fumigatus which we refer to as invasive aspergillosis-on-chip (IAC) model. The model creates
an ALI composed of an alveolar epithelial cell … us to track interactions between primary …

[HTML][HTML] Suppression of Aspergillus fumigatus germination by neutrophils is enhanced by endothelial-derived CSF3 production

W Zhang, D He, Y Wei, S Shang, D Li… - Frontiers in …, 2022 - frontiersin.org
… This study provides additional insight into the interaction between neutrophils/stromal cells
Aspergillus fumigatus Culture Aspergillus fumigatus strain IFM40808 was used in this study. …