The anti-VEGF (R) drug discovery legacy: improving attrition rates by breaking the vicious cycle of angiogenesis in cancer
… , VEGF production is related to vasodilation; VEGFR-2 is also related to cell survival and
migration, and VEGFR-1 is … soluble neuropilin-1 (sNRP-1), which is a co-receptor for VEGF in …
migration, and VEGFR-1 is … soluble neuropilin-1 (sNRP-1), which is a co-receptor for VEGF in …
[PDF][PDF] Temporal Vascular Endothelial Growth Factor Sub-type gene Switching in SARS-CoV Pathogenesis. Interpretation through in vivo Murine C57BL Models
… that VEGF-A and VEGF-B share the receptor VEGFR-1, we … CoV-2 spike protein can co-op
the VEGF-A/neuropilin-1 … rise in VEGF-A results in angiogenesis from VEGFR-2 stimulation. …
the VEGF-A/neuropilin-1 … rise in VEGF-A results in angiogenesis from VEGFR-2 stimulation. …
Peripheral vascular disease: preclinical models and emerging therapeutic targeting of the vascular endothelial growth factor ligand-receptor system
… isoforms, and the pathways altered by modulating different VEGF receptor-ligand interactions,
… including in vitro or ex vivo macrophage conditioned medium or human plasma samples …
… including in vitro or ex vivo macrophage conditioned medium or human plasma samples …
[HTML][HTML] A multiscale computational model of angiogenesis after traumatic brain injury, investigating the role location plays in volumetric recovery
… VEGF is of particular interest after a traumatic brain injury (TBI), as it re-… a computational
model that quickly simulates vessel growth and recovery by coupling VEGF and its interactions …
model that quickly simulates vessel growth and recovery by coupling VEGF and its interactions …
Regulation of cells of the arterial wall by hypoxia and its role in the development of atherosclerosis
S Norda, R Papadantonaki - Vasa, 2022 - econtent.hogrefe.com
… -4) and neuropilins (NRPs) acting as VEGF co-receptors [119]. … VEGFR-1 embodies a tyrosine
kinase with decreased activity due to its function as decoy receptor antagonizing VEGFR-2 …
kinase with decreased activity due to its function as decoy receptor antagonizing VEGFR-2 …
Temporal Vascular Endothelial Growth Factor Sub-type Gene Switching in SARS-CoV-related Inflammation-Basis for a Dual Gene Biomarker Approach
… that VEGF-A and VEGF-B share the receptor VEGFR-1, we … CoV-2 spike protein can co-op
the VEGF-A/neuropilin-1 … rise in VEGF-A results in angiogenesis from VEGFR-2 stimulation. …
the VEGF-A/neuropilin-1 … rise in VEGF-A results in angiogenesis from VEGFR-2 stimulation. …
[HTML][HTML] Systems biology will direct vascular-targeted therapy for obesity
Y Fang, T Kaszuba, PI Imoukhuede - Frontiers in Physiology, 2020 - frontiersin.org
… requires appropriate computational models and quantitative … A recent study of VEGF-A
(xxx)b mRNA in vivo further … healthy mouse skeletal muscle and tumor xenograft models, where …
(xxx)b mRNA in vivo further … healthy mouse skeletal muscle and tumor xenograft models, where …
Affinity-enhanced multimeric VEGF (vascular endothelial growth factor) and PlGF (placental growth factor) variants for specific adsorption of sFlt-1 to restore …
M Matin, M Mörgelin, J Stetefeld, B Schermer… - …, 2020 - Am Heart Assoc
… affinity for sFlt-1 in the absence of heparin or neuropilin 1. … VEGF isoform VEGF 95 only
displays reduced interaction with … We introduce the first in vivo applicable apheresis system for …
displays reduced interaction with … We introduce the first in vivo applicable apheresis system for …
Neuropilin-2 as a Novel Angiogenic Player: deciphering the contributions of neuropilin-2 during developmental and pathological angiogenesis
C Benwell - 2022 - ueaeprints.uea.ac.uk
… depletion in vitro, … interacting with high affinity to two transmembrane bound cell surface
receptor families; the VEGFR family of tyrosine kinase receptors, notably VEGFR-1 and VEGFR-2…
receptor families; the VEGFR family of tyrosine kinase receptors, notably VEGFR-1 and VEGFR-2…
Angiogenesis in hepatocellular carcinoma; pathophysiology, targeted therapy, and role of imaging
… with complex but balanced interactions between pro-angiogenic … Membrane bound factors
include neuropilin receptors (NRP)… of these receptors: VEGFR-1, VEGFR-2, and VEGFR-3. …
include neuropilin receptors (NRP)… of these receptors: VEGFR-1, VEGFR-2, and VEGFR-3. …