Characterising the role of neuropilin-1 in claudin-low breast cancer
LR Lynam - 2023 - eprints.qut.edu.au
… In-vitro and In-vivo studies have implicated NRP1 in the regulation of EMT and tumour …
The interactions of NRP1 with semaphorins and vascular endothelial growth factors (VEGF) are …
The interactions of NRP1 with semaphorins and vascular endothelial growth factors (VEGF) are …
Vascular endothelial growth factor receptors [VEGFR] as target in breast cancer treatment: current status in preclinical and clinical studies and future directions
M Malekan, MA Ebrahimzadeh - Current Topics in Medicinal …, 2022 - ingentaconnect.com
… that expressing both VEGFR-1 and VEGFR-2 in the cell lines … vascular development after
interaction with VEGFR-2 [31, 57]. … effects of wogonin in vitro and in vivo revealed that this agent …
interaction with VEGFR-2 [31, 57]. … effects of wogonin in vitro and in vivo revealed that this agent …
Preparation, In Vitro Affinity, and In Vivo Biodistribution of Receptor-Specific 68Ga-Labeled Peptides Targeting Vascular Endothelial Growth Factor Receptors
P Barta, R Kamaraj, M Kucharova, Z Novy… - Bioconjugate …, 2022 - ACS Publications
… into the active sites of VEGFR-1-D2 and VEGFR-2-D2, … 2 was detected for the interaction
with VEGFR-2. This result is … was used for computational biomolecular interaction studies (…
with VEGFR-2. This result is … was used for computational biomolecular interaction studies (…
[HTML][HTML] New antiproliferative 3-substituted oxindoles inhibiting EGFR/VEGFR-2 and tubulin polymerization
… three isoforms of VEGF receptors, namely VEGFR-1 (Flt-1), … the same binding interactions
inside the VEGFR-2’s binding … the furthermost practical computational approaches to offer a …
inside the VEGFR-2’s binding … the furthermost practical computational approaches to offer a …
Affinity-enhanced multimeric VEGF (vascular endothelial growth factor) and PlGF (placental growth factor) variants for specific adsorption of sFlt-1 to restore …
M Matin, M Mörgelin, J Stetefeld, B Schermer… - …, 2020 - Am Heart Assoc
… high affinity for sFlt-1 in the absence of heparin or neuropilin 1. … VEGF isoform VEGF 95 only
displays reduced interaction with … 165 did not improve binding in contrast to computational …
displays reduced interaction with … 165 did not improve binding in contrast to computational …
[PDF][PDF] Temporal Vascular Endothelial Growth Factor Sub-type gene Switching in SARS-CoV Pathogenesis. Interpretation through in vivo Murine C57BL Models
… that VEGF-A and VEGF-B share the receptor VEGFR-1, we … CoV-2 spike protein can co-op
the VEGF-A/neuropilin-1 … rise in VEGF-A results in angiogenesis from VEGFR-2 stimulation. …
the VEGF-A/neuropilin-1 … rise in VEGF-A results in angiogenesis from VEGFR-2 stimulation. …
[HTML][HTML] Aflibercept Off-Target Effects in Diabetic Macular Edema: An In Silico Modeling Approach
M Blanot, RP Casaroli-Marano… - International Journal of …, 2024 - mdpi.com
… We obtained computational models of the effect of IAI on … DME pathophysiological processes,
such as neuropilins (NRPs), … by VEGF-A, VEGF-B, PlGF, and Gal-1 by interacting with their …
such as neuropilins (NRPs), … by VEGF-A, VEGF-B, PlGF, and Gal-1 by interacting with their …
Characterization of Novel Anti-VEGFR Antibodies to Develop Agonists Targeting Mesoderm Differentiation
S Mishra - 2021 - search.proquest.com
… Table 3: Summary of in vitro binding constants for the … but its activation indicates the interaction
of endothelial cells with … VEGFR-1 and VEGFR-2 agonists that can replace VEGF. Natural …
of endothelial cells with … VEGFR-1 and VEGFR-2 agonists that can replace VEGF. Natural …
[HTML][HTML] Quinazolines and thiazolidine-2, 4-dions as SARS-CoV-2 inhibitors: repurposing, in silico molecular docking and dynamics simulation
… VEGFR-1 (sFlt-1) activation appears to be as an endogenous VEGF inhibitor, while VEGFR-2
… On the other hand using VEGFA, a physiological ligand for the b1b2 pocket in neuropilin-1 …
… On the other hand using VEGFA, a physiological ligand for the b1b2 pocket in neuropilin-1 …
[HTML][HTML] The anti-VEGF (R) drug discovery legacy: improving attrition rates by breaking the vicious cycle of angiogenesis in cancer
… , VEGF production is related to vasodilation; VEGFR-2 is also related to cell survival and
migration, and VEGFR-1 is … soluble neuropilin-1 (sNRP-1), which is a co-receptor for VEGF in …
migration, and VEGFR-1 is … soluble neuropilin-1 (sNRP-1), which is a co-receptor for VEGF in …