New trinuclear nickel (II) complexes as potential topoisomerase I/IIα inhibitors: in vitro DNA binding, cleavage and cytotoxicity against human cancer cell lines
… The electronic spectra in DNA interaction studies and of metal complexes were recorded on
a … stable chelate complex with Ni(II), also inhibits DNA cleavage, suggesting Ni(II) complex …
a … stable chelate complex with Ni(II), also inhibits DNA cleavage, suggesting Ni(II) complex …
In vitro evaluations of biomolecular interactions, antioxidant and anticancer activities of Nickel (II) and Copper (II) complexes with 1: 2 coordination of anthracenyl …
KS Neethu, S Sivaselvam, M Theetharappan… - Inorganica Chimica …, 2021 - Elsevier
… Choosing a suitable ligand that can easily coordinate with nickel/copper and forms a
stable complex, which could communicate with DNA receptors is vital. Schiff base metal …
stable complex, which could communicate with DNA receptors is vital. Schiff base metal …
New manganese (II), iron (II), cobalt (II), nickel (II) and copper (II) saccharinate complexes of 2, 6-bis (2-benzimidazolyl) pyridine as potential anticancer agents
… complexes are stable in both DMSO and saline, retaining their structural integrity in solution
… to elucidate the binding modes and interactions of the complexes with DNA. The molecular …
… to elucidate the binding modes and interactions of the complexes with DNA. The molecular …
Coordination properties of the zinc domains of BigR4 and SmtB proteins in nickel systems─ designation of key donors
A Rola, P Potok, R Wieczorek, M Mos… - Inorganic …, 2022 - ACS Publications
… alanine, cause a decrease in the stability of Ni(II) complexes. Surprisingly, the lack of His102
… energy as long as we take into account the same type of interactions. One could expect that …
… energy as long as we take into account the same type of interactions. One could expect that …
Tuning Receptor Properties of Metal–Amyloid Beta Complexes. Studies on the Interaction between Ni(II)–Aβ5–9 and Phosphates/Nucleotides
A Tobolska, NE Wezynfeld, UE Wawrzyniak… - Inorganic …, 2021 - ACS Publications
… In the next step, we calculated the stability constants of Ni(II)–Aβ 5–9 complexes. Their
values for the most reliable coordination model are depicted in Table 1, whereas the respective …
values for the most reliable coordination model are depicted in Table 1, whereas the respective …
[PDF][PDF] The evaluation of the anti-histone deacetylase, antibacterial, antioxidant and cytotoxic activities of synthetic N, N´-ethylenebis (α methylsalicylideneiminate) …
F Mosalanezhad, A Asadzadeh… - Iranian Journal of …, 2022 - ijcce.ac.ir
… Comparatively, the interaction energies obtained here have a … the α,ά-Me2-salen forms a
more stable complex than SAHA. … the studied complexes, α,ά-Me2-salen and Ni (II) complex …
more stable complex than SAHA. … the studied complexes, α,ά-Me2-salen and Ni (II) complex …
Collaboration between 3d-4f metal centers of heterodimetallic Ni (II)-Gd (III) complex in catecholase activity and interaction with FS-DNA & BSA
… stability study on the Ni-Gd complex was done, and the results confirmed that the Ni-Gd
complex did not decompose and was stable at … in its structure. The very small hyperchromicity in …
complex did not decompose and was stable at … in its structure. The very small hyperchromicity in …
Key role of histidine residues orientation in affinity binding of model pentapeptides with Ni2+ ions: A theoretical supported experimental study
K Żamojć, D Wyrzykowski, G Sabatino… - Journal of Molecular …, 2021 - Elsevier
… the most likely structures of the complexes of the peptides p1-p4 with Ni 2+ ions. It … 2
thermodynamically stable complexes with Ni 2+ cation. In particular, we observed that the interaction …
thermodynamically stable complexes with Ni 2+ cation. In particular, we observed that the interaction …
Antiproliferative activity of nickel (II), palladium (II) and zinc (II) thiosemicarbazone complexes
M Carcelli, S Montalbano, D Rogolino, V Gandin… - Inorganica Chimica …, 2022 - Elsevier
… Nichel complexes are stable in DMSO solution over time, … nickel complex of citronellal
thiosemicarbazone interacts directly with the DNA backbone and/or histones, causing a structural …
thiosemicarbazone interacts directly with the DNA backbone and/or histones, causing a structural …
Inhibition of histone deacetylases, topoisomerases and epidermal growth factor receptor by metal-based anticancer agents: Design & synthetic strategies and their …
… chromatin by the interaction of DNA with positively charged histone core, … stability constants
of bis-hydroxamato complexes of Cu(II), Ni(II), Zn(II) and tris-hydroxamato complex of Fe(III…
of bis-hydroxamato complexes of Cu(II), Ni(II), Zn(II) and tris-hydroxamato complex of Fe(III…