The interaction between pulmonary fibrosis and COVID-19 and the application of related anti-fibrotic drugs

H Shen, N Zhang, Y Liu, X Yang, Y He, Q Li… - Frontiers in …, 2022 - frontiersin.org
idiopathic pulmonary fibrosis or non-idiopathic pulmonary … of pulmonary fibrosis, which
is anti-inflammatory effect may be … the indications for drug use, carefully select the anti-fibrosis

The protective potential of alpha lipoic acid on amiodarone-induced pulmonary fibrosis and hepatic injury in rats

G Ibrahim Fouad, M R. Mousa - Molecular and Cellular Biochemistry, 2021 - Springer
… transforming growth factor beta-1 (TGF-β1), interferon-γ (IFN-γ), … is to demonstrate the protective
effect and the multifactorial … the lung homogenate as an indication of collagen deposition …

Lenalidomide attenuates post-inflammation pulmonary fibrosis through blocking NF-κB signaling pathway

X Li, Q Liang, S Gao, Q Jiang, F Zhang, R Zhang… - International …, 2022 - Elsevier
… the effect of lenalidomide on post-inflammation fibrosis. In vitro … -6 while stimulated the
anti-fibrotic cytokines interferon-γ (IFN-γ) … new indications and provide more choices for pulmonary

Favipiravir ameliorates bleomycin-induced pulmonary fibrosis by reprogramming M1/M2 macrophage polarization

R Zhang, Q Jiang, S Gao, H Zhang, Q Xia, B Liu… - International …, 2024 - Elsevier
… , IL-12, interferon-γ (IFN-γ), monocyte chemoattractant protein 1 (… The thermal stability of JAK2
was quantified as indication. (D… In the future work, we intend to study the effect of favipiravir …

Sildenafil beyond erectile dysfunction and pulmonary arterial hypertension: Thinking about new indications

M Ala, R Mohammad Jafari… - Fundamental & clinical …, 2021 - Wiley Online Library
… the ultimate effects of sildenafil. The aim of this review was to describe the effects of sildenafil
… days) reduced lung fibrosis in a rat model of pulmonary fibrosis by reducing the expression …

Therapeutic Strategies for Idiopathic Pulmonary Fibrosis–Thriving Present and Promising Tomorrow

N Gupta, M Paryani, S Patel, A Bariya… - The Journal of …, 2024 - Wiley Online Library
effect on dyspnea, which is a severe symptom of IPF. Pulmonary hypertension acts as a
stumbling indication in patients … Predictive value of interferon-γ release assays for incident active …

Icariside Ⅱ attenuates bleomycin-induced pulmonary fibrosis by modulating macrophage polarization

L Deng, B Ouyang, H Shi, F Yang, S Li, C Xie… - Journal of …, 2023 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a debilitating and … a therapeutic effect on
bleomycin-induced pulmonary fibrosis (… imaging revealed various indications of severe fibrotic

Total synthesis of glycosylated human interferon-γ

X Wang, AS Ashhurst, LJ Dowman, EE Watson… - Organic …, 2020 - ACS Publications
… for a range of other indications in clinical and preclinical … cancer, scleroderma, idiopathic
pulmonary fibrosis, and fungal … of expressed hIFN-γ, the effect of glycosylation on the structure …

Matrix metalloproteinases inhibitors in idiopathic pulmonary fibrosis: Medicinal chemistry perspectives

L Yue, Y Shi, X Su, L Ouyang, G Wang, T Ye - European Journal of …, 2021 - Elsevier
… MMPs not only play their own degradation effects in modulating physiological processes but
… role in the entire process of pulmonary fibrosis (both antifibrotic and profibrotic effects). The …

Customizable resveratrol spray-dried micro-composites for inhalation as a promising contender for treatment of idiopathic pulmonary fibrosis

S Ahmed, M Mansour, RAH Ishak… - International Journal of …, 2023 - Elsevier
… decrease the drug dose, reduce systemic side effects related to the drug and improve patient
… The mass median aerodynamic diameter (MMAD) of the SDCMs, which gives an indication