Targeting Ferroptosis for Lung Diseases: Exploring Novel Strategies in Ferroptosis‐Associated Mechanisms

TL Ma, Y Zhou, C Wang, L Wang… - Oxidative medicine …, 2021 - Wiley Online Library
… on the pathogenesis of idiopathic pulmonary fibrosis (IPF) … Current knowledge argues that
interferon-γ (IFNγ) produced by … -1 (Lip-1) has a significant therapy effect on RILF mice. Lip-…

Correlation between BAL CXCR3 chemokines and lung allograft histopathologies: A multicenter study

MY Shino, N Li, JL Todd, ML Neely… - American Journal of …, 2021 - Wiley Online Library
… are CXC chemokines induced by interferon-γ and act as potent … univariable mixed effects
models with random effect variables … to affect MFIs (clinical indication, lavage volume instilled, …

The linkage between inflammation and fibrosis in muscular dystrophies: The axis autotaxin–lysophosphatidic acid as a new therapeutic target?

FS Gallardo, A Córdova-Casanova… - Journal of cell …, 2021 - Springer
… It analyzes experimental evidence of the effects of the ATX/… as lipopolysaccharides from
bacteria, and interferon-γ (IFN-γ) … are strong indications that these cells can promote fibrosis. …

Assessing the Potential of N-Butyl-l-deoxynojirimycin (l-NBDNJ) in Models of Cystic Fibrosis as a Promising Antibacterial Agent

A Esposito, A Rossi, M Stabile, G Pinto… - ACS Pharmacology & …, 2024 - ACS Publications
… Furthermore, we also performed in vitro studies to assess the effect of l-NBDNJ on P. … , C2,
and C3 complement system components and cytokines as interferon-γ, IL-6, and TNF-α, useful …

Pulmonary prophylactic impact of bee venom against alterations induced by gamma irradiation via TLR4/NF-κB signaling pathway in rats

DM Lotfy, HF Hasan, DM Mostafa - Toxin Reviews, 2022 - Taylor & Francis
… Lactic acid is elevated in idiopathic pulmonary fibrosis and induces myofibroblast
differentiation via pH-dependent activation of transforming growth factor-β. American journal of …

TRPA1: A promising target for pulmonary fibrosis?

C Li, J Xu, A Abdurehim, Q Sun, J Xie… - European Journal of …, 2023 - Elsevier
… prognosis but also lessen the broader societal and economic impact. … Th1 cells release
Interferon-γ (IFN-γ), which activates … All indications suggest that this seemingly coincidental …

The interplay of fibroblasts, the extracellular matrix, and inflammation in scar formation

L Moretti, J Stalfort, TH Barker, D Abebayehu - Journal of Biological …, 2022 - ASBMB
… factors contributing to fibrosis provides new research directions … idiopathic pulmonary
fibrosis, liver cirrhosis, systemic sclerosis, progressive kidney disease, and cardiovascular fibrosis

It's not all about inhaled treatment: challenges with oral therapy in paediatric respiratory medicine

A Sareen, M Ramphul, JM Bhatt - Breathe, 2021 - Eur Respiratory Soc
… and the relative complexities of her treatment and the impacts … Three nights a week she has
an injection of interferon-γ. … Prednisolone, amongst other indications, is used for the treatment …

Lysophospholipid mediators in health and disease

K Kano, J Aoki, T Hla - Annual Review of Pathology …, 2022 - annualreviews.org
… had positive effects on the progression of lung fibrosis in … for patients with idiopathic
pulmonary fibrosis, and GLPG1690 … However, additional clinical trials for other indications have …

N-acetylcysteine as adjuvant therapy for COVID-19–a perspective on the current state of the evidence

KK Wong, SWH Lee, KP Kua - Journal of inflammation research, 2021 - Taylor & Francis
… Here, we review evidence concerning the effects of N-… T‐lymphocyte clones and interferon-γ
generation. Citation55 … risk factors with idiopathic pulmonary fibrosis, the effectiveness of N-…