Cysteine oxidation of copper transporter CTR1 drives VEGFR2 signalling and angiogenesis

A Das, D Ash, AY Fouda, V Sudhahar, YM Kim… - Nature cell …, 2022 - nature.com
… endothelial growth factor receptor type 2 (VEGFR2, also known as KDR and FLK1) signalling
in … how ROS regulate VEGFR2 endocytosis to activate VEGFR2 signalling remains unclear. …

[HTML][HTML] Targeting tumor-associated MUC1 overcomes anoikis-resistance in pancreatic cancer

M Bose, A Sanders, C De, R Zhou, P Lala… - Translational …, 2023 - Elsevier
growth factors such as Epidermal growth factor (EGF), Fibroblast … of membrane proteins
triggers their internalization and … tyrosine-phosphorylation and ubiquitination of tMUC1, thus …

Destruction or reconstruction: a subtle liaison between the proteolytic and signaling role of protein ubiquitination in spermatogenesis

G Berruti - Molecular Mechanisms in Spermatogenesis, 2021 - Springer
Receptor-mediated endocytosis is often associated to multi-… separated, the two systems
intersect and communicate; the … , cooperate to regulate histone ubiquitination during meiosis to …

TRAF6 modulates PD-L1 expression through YAP1-TFCP2 signaling in melanoma

X Liu, L Wang, Y Han, H Tsai, F Shu, Z Xu, C He, H Zhu… - bioRxiv, 2022 - biorxiv.org
… cells and found no obvious signal of PD-L1 K63 ubiquitination by … We took the intersection
of 6839 differentially expressed … factors (TFs) documented in the Animal Transcription Factor

Epidermal growth factor protects against high glucose-induced podocyte injury possibly via modulation of autophagy and PI3K/AKT/mTOR signaling pathway through …

Y Sun, M Deng, X Ke, X Lei, H Ju, Z Liu… - … Syndrome and Obesity, 2021 - Taylor & Francis
… (A) The venn diagram shows the intersection between … EGF is the typical epidermal growth
factor receptor (EGFR) ligand, … , inhibition of EGFR ubiquitination ameliorated hyperglycemia …

[HTML][HTML] The growth hormone receptor interacts with transcriptional regulator HMGN1 upon GH-induced nuclear translocation

L Jain, MH Vickers, B Jacob, MJ Middleditch… - … and Signaling, 2023 - Springer
… For example, the epidermal growth factor receptor (EGFR), … a Venn diagram showing the
intersection of known gene targets of … proteins involved in ubiquitination following GH treatment. …

The atypical Rho GTPase RhoU interacts with intersectin-2 to regulate endosomal recycling pathways

O Gubar, P Croisé, S Kropyvko… - Journal of cell …, 2020 - journals.biologists.com
… structures where it governs cell signaling, differentiation and … To probe for this, we analyzed
EGF receptor endocytosis by … /ml TRITC-conjugated epidermal growth factor (EGF, Thermo …

[HTML][HTML] Regulation of three key kinases of brassinosteroid signaling pathway

J Mao, J Li - International Journal of Molecular Sciences, 2020 - mdpi.com
… the nucleus through two master transcription factors, bri1-EMS … regulate BRI1 endocytosis
and downstream BR signaling. … ubiquitination of BRI1 [112] while its packaging into MVBs is …

Revisiting the intersection of microglial activation and neuroinflammation in Alzheimer's disease from the perspective of ferroptosis

M Wang, G Tang, C Zhou, H Guo, Z Hu, Q Hu… - Chemico-Biological …, 2023 - Elsevier
… Physiologically, iron recycling precisely controls iron … by transferrin receptor 1 (TfR1) and
transported into cells via endocytosis [8]. … , which triggers the internalization, ubiquitination, and …

Investigating the regulation of Fast Endophilin-Mediated Endocytosis

A Casamento - 2024 - discovery.ucl.ac.uk
… and signalling and, additionally, regulates the internalization … translation modifications (phosphorylation
or ubiquitination); therefore, … Growth Factor receptors can be trafficked via FEME: …