The role of mitochondria in acute kidney injury and chronic kidney disease and its therapeutic potential
X Zhang, E Agborbesong, X Li - International journal of molecular …, 2021 - mdpi.com
… Mitochondria are intracellular organelles that contain an inner and outer membrane, with an
… connects mitochondria to other cellular organelles, including the endoplasmatic reticulum (…
… connects mitochondria to other cellular organelles, including the endoplasmatic reticulum (…
Mitochondrial quality control in kidney injury and repair
C Tang, J Cai, XM Yin, JM Weinberg… - Nature Reviews …, 2021 - nature.com
… of acute kidney injury (AKI) and chronic kidney disease, as well as in abnormal … Mitochondria
are intracellular organelles that have key roles in the production of ATP, the regulation of …
are intracellular organelles that have key roles in the production of ATP, the regulation of …
Tubular mitochondrial dysfunction, oxidative stress, and progression of chronic kidney disease
M Fontecha-Barriuso, AM Lopez-Diaz… - Antioxidants, 2022 - mdpi.com
… Mitochondrial Function in Healthy Kidneys Mitochondria are intracellular organelles … ;
control cell death, inflammation, and intracellular calcium; traffic phospholipids; regulate danger …
control cell death, inflammation, and intracellular calcium; traffic phospholipids; regulate danger …
Mitochondrial pathophysiology on chronic kidney disease
… intracellular GSH content. The glutathione redox cycle is the critical antioxidant mechanism
found in several intracellular organelles… , since ascorbate can maintain intracellular GSH [273]…
found in several intracellular organelles… , since ascorbate can maintain intracellular GSH [273]…
The multifaceted role of kidney tubule mitochondrial dysfunction in kidney disease development
More than 800 million people suffer from kidney disease. Genetic studies and follow-up
animal models and cell biological experiments indicate the key role of proximal tubule …
animal models and cell biological experiments indicate the key role of proximal tubule …
Mitochondrial redox signaling and oxidative stress in kidney diseases
… Mitochondria are essential organelles in physiology and kidney diseases, because they … In
line with this, the redox-sensitive extracellular regulated kinase 2 (ERK2) protein mediates the …
line with this, the redox-sensitive extracellular regulated kinase 2 (ERK2) protein mediates the …
Effects of chronic kidney disease and uremic toxins on extracellular vesicle biology
L Yaker, S Kamel, J Ausseil, A Boullier - Toxins, 2020 - mdpi.com
… in cytoplasmic proteins, organelle-associated proteins and housekeeping factors, whereas
VSMC-derived exosomes contain more cell adhesion and extracellular matrix proteins [46]. …
VSMC-derived exosomes contain more cell adhesion and extracellular matrix proteins [46]. …
Mitochondrial dysfunction in kidney disease and uremic sarcopenia
K Takemura, H Nishi, R Inagi - Frontiers in Physiology, 2020 - frontiersin.org
… Mitochondria are major intracellular organelles with a variety of critical roles, such as … of
reactive oxygen species, maintenance of intracellular calcium homeostasis, and the regulation of …
reactive oxygen species, maintenance of intracellular calcium homeostasis, and the regulation of …
Oxidative stress and mitochondrial dysfunction in chronic kidney disease
HJ Ho, H Shirakawa - Cells, 2022 - mdpi.com
… , alterations in bioenergetics, and organelle stress cause renal diseases [7]. Mitochondrial
… stress by enhancing MnSOD and inhibiting intracellular ROS generation, suggesting that …
… stress by enhancing MnSOD and inhibiting intracellular ROS generation, suggesting that …
The role of mitochondrial fission proteins in mitochondrial dynamics in kidney disease
L Qin, S Xi - International Journal of Molecular Sciences, 2022 - mdpi.com
… elevated intracellular ROS, … organelles with diverse roles and are involved in a variety of
biological functions. Mitochondria can regulate other organelles, and, in turn, other organelles …
biological functions. Mitochondria can regulate other organelles, and, in turn, other organelles …