Porphyromonas gingivalis: Immune Subversion Activities and Role in Periodontal Dysbiosis

G Hajishengallis, PI Diaz - Current oral health reports, 2020 - Springer
… by which Porphyromonas gingivalis interacts with community … gingivalis has been shown
to induce cell death and DNA … the production of inflammatory cytokines. Contrary to MYD88, …

Roles of Porphyromonas gingivalis and its virulence factors in periodontitis

W Xu, W Zhou, H Wang, S Liang - Advances in protein chemistry and …, 2020 - Elsevier
… One example of direct interaction is that P. … TLR2 and induce the production of pro-inflammatory
cytokines, such … /macrophages, resulting in extracellular signal-regulated kinase 1/2 (…

Porphyromonas gingivalis adopts intricate and unique molecular mechanisms to survive and persist within the host: a critical update

A Chopra, SG Bhat, K Sivaraman - Journal of Oral Microbiology, 2020 - Taylor & Francis
interaction activates a cascade of signaling pathways that cause release of proinflammatory
cytokines … and decrease the release of cytokine-induced neutrophil chemoattractant (CINC) …

[HTML][HTML] Local and Systemic Effects of Porphyromonas gingivalis Infection

WA Chen, Y Dou, HM Fletcher, DS Boskovic - Microorganisms, 2023 - mdpi.com
… TLR2 signaling for the induction of proinflammatory cytokines and for … gingivalis interaction
with platelets can induce platelet activation and subsequent aggregation [261]. Intracellular

[HTML][HTML] Macrophages: A communication network linking Porphyromonas gingivalis infection and associated systemic diseases

J Lin, D Huang, H Xu, F Zhan, XL Tan - Frontiers in Immunology, 2022 - frontiersin.org
… , we summarize recent discoveries on the interaction of P. … Due to the complex interplay
of cytokines, metabolites and … gingivalis to induce macrophages M1 polarizations, blocking …

Effects of Endotoxin Tolerance Induced by Porphyromonas gingivalis Lipopolysaccharide on Inflammatory Responses in Neutrophils

J Gu, Y Liu, X Zhu, J Qiu, Y Sun - Inflammation, 2020 - Springer
… respiratory burst in neutrophils upon single or repeated P. … The protein expressions of
extracellular signal–regulated kinase1… the amounts of the abovementioned cytokines induced by …

[HTML][HTML] Macrophages immunomodulation induced by Porphyromonas gingivalis and oral antimicrobial peptides

BE Blancas-Luciano, J Zamora-Chimal… - Odontology, 2023 - Springer
… The presence of inflammatory cytokines and the persistence of P. … , or the interaction
with cellular receptors that induce the phosphorylation adaptor proteins in intracellular signal

[HTML][HTML] Porphyromonas gingivalis induction of TLR2 association with Vinculin enables PI3K activation and immune evasion

K Pandi, S Angabo, J Gnanasekaran, H Makkawi… - PLoS …, 2023 - journals.plos.org
… importance of induced TLR2 intracellular interacting partners … effects on intracellular signaling
by regulating signaling … recruitment of MyD88 for LPS-induced cytokine secretion [40]. The …

Molecular strategies underlying Porphyromonas gingivalis virulence

IL Silva, E Cascales - Journal of Molecular Biology, 2021 - Elsevier
… responses and reducing cytokine production, promoting tissue … to DNA, but interacts with
SigP, and this interaction is necessary for … gingivalis induces neurological disorders is of critical …

Porphyromonas gingivalis outside the oral cavity

S Bregaint, E Boyer, SB Fong, V Meuric… - Odontology, 2022 - Springer
… expression of a variety of molecular adhesives (intercellular … , via interaction with iron
metabolism, induction by LPS of … induce the production of pro-inflammatory cytokines and the …