Porphyromonas gingivalis lipopolysaccharide induced RIPK3/MLKL-mediated necroptosis of oral epithelial cells and the further regulation in macrophage activation

F Geng, J Liu, C Yin, S Zhang, Y Pan… - Journal of Oral …, 2022 - Taylor & Francis
… mediated by the receptor-interacting protein serine-threonine … as necroptosis, intracellular
alarm signals are induced as … , we first tested cytokines expression stimulated by DAMPs in …

[HTML][HTML] Porphyromonas gingivalis induces an inflammatory response via the cGAS-STING signaling pathway in a periodontitis mouse model

R Bi, Y Yang, H Liao, G Ji, Y Ma, L Cai, J Li… - Frontiers in …, 2023 - frontiersin.org
gingivalis OMVs activate the extracellular signal-regulated kinase (… cytokines can be
produced in response to P. … and its interaction with inflammation is worth further exploration. …

Lipoteichoic acid of Enterococcus faecalis interferes with Porphyromonas gingivalis lipopolysaccharide signaling via IRAK‐M upregulation in human periodontal …

J Im, JE Baik, D Lee, KY Kum, CH Yun… - Molecular Oral …, 2020 - Wiley Online Library
… Here, we examined the interaction between Ef.LTA and Pg.LPS on IL-8 induction in
human … -M), A20, suppressor of cytokine signaling (SOCS)-1, and Toll-interacting protein (TOLLIP); …

The Effects of Porphyromonas gingivalis on Inflammatory and Immune Responses and Osteogenesis of Mesenchymal Stem Cells

J Yu, S Chen, S Lei, F Li, Y Wang, X Shu… - Stem Cells and …, 2021 - liebertpub.com
… These functions include the secretion of cytokines and … lipid A species that functionally
interact with both toll-like … inflammatory microenvironment induced by Porphyromonas gingivalis

[HTML][HTML] … derived from Porphyromonas gingivalis and Escherichia coli: Differential and interactive effects on novelty-induced hyperlocomotion, blood cytokine levels …

Y Aono, K Saito, H Kawashima, A Watanabe, T Kono… - Plos one, 2024 - journals.plos.org
… plausible that variations in receptors interacting with Pg-LPS … Pg-LPS induces effects on
extracellular cytokine levels that … -10 in mouse brain was decreased after LPS treatment [31] and …

[HTML][HTML] HSP90AA1 promotes the inflammation in human gingival fibroblasts induced by Porphyromonas gingivalis lipopolysaccharide via regulating of autophagy

H Zhang, J Huang, XS Fan, RJ Miao, YW Wang - BMC Oral Health, 2022 - Springer
… by directly interacting with AKT/mTOR signaling pathway. … -1β, IL-6, TNF-α in Pg-LPS induced
HGFs is mediated by the … and intracellular ROS levels were significantly reduced after cells …

[HTML][HTML] Porphyromonas gingivalis triggers the shedding of inflammatory endothelial microvesicles that act as autocrine effectors of endothelial dysfunction

IM Bugueno, F Zobairi El-Ghazouani, F Batool… - Scientific Reports, 2020 - nature.com
cytokines induction (Fig… upon pathogen infection appear to be another target since EMV
are able to concentrate at endothelial sites where flow disturbance favors enhanced interactions

Molecular hydrogen suppresses Porphyromonas gingivalis lipopolysaccharide-induced increases in interleukin-1 alpha and interleukin-6 secretion in human gingival …

Y Saitoh, N Yonekura, D Matsuoka… - Molecular and Cellular …, 2022 - Springer
… cells are thought to be induced through the Nrf2 pathway and the interaction between IL-1
and IL-6. This important … 2 The effect of Pg LPS treatment on intracellular oxidative stress level. …

Porphyromonas gingivalis: where do we stand in our battle against this oral pathogen?

KC Howard, OA Gonzalez… - RSC Medicinal …, 2021 - pubs.rsc.org
… periodontal pathogenic bacteria that induces chronic inflammation. … could be enhanced by
synergistic interactions between P. … the production of inflammatory cytokines. The virulence of …

… Porphyromonas gingivalis Lipopolysaccharide‐Induced Matrix Metalloproteinase‐1 and Proinflammatory Cytokines by Suppressing the TLR4/NF‐κB Signaling …

JM Kim, EM Noh, YO You, MS Kim… - BioMed Research …, 2022 - Wiley Online Library
… response induced by PG-LPS relies on its interaction with Toll… , mediates multiple intracellular
signaling pathways following … After 4 washes, APMA (p-aminophenylmercuric acetate) was …