Frontiers | A multidimensional investigation of the relationship between skin-mediated
somatosensory signals, emotion regulation and behavior problems in autistic children Skip to …

… Chapter 3 describes the somatosensory deficits reported in ASD, in both humans and in
some of the most widely used mouse models of ASD. This chapter provides information on the …

… of ASD brains, with higher levels of local connectivity and lower … the somatosensory area,
were also found in this study in ex vivo … Although local intra-insular pathways were not clearly …

… of and responses to somatosensory stimuli, such as … In autistic children, sensory hypo-responsiveness
and … correlates of autism indicate differences in thalamic connectivity in autism. For …

… by intensive intra-insular connectivity but differ in connectivity to … -scale network called the
social decision-making network (… behavior and stress responsiveness through distinct receptor …

… the atypical visual responsiveness seen in children with ASD and … Somatosensory
discrimination refers to discrimination of the … Neural connectivity studies of individuals with ASD …

… The heterogeneity of intra-insular connectivity within the ASD population is evidenced by the
… Differences in HPA-axis and heart rate responsiveness to psychosocial stress in children …

… Intra-insular connections bring this somatosensory information towards the anterior insula,
where it is processed with prefrontal and limbic regions to provide emotional and salience …

… By elucidating the impact of mutations in ASD candidate genes on somatosensory circuits
and … Intrainsular connectivity and somatosensory responsiveness in young children with ASD. …

… such that individuals who are hyper-responsive tend to be hypo-responsive as well [12] (Fig…
in autism also suggest that tactile reactivity patterns relate to white matter connections within …