[HTML][HTML] Exploring the Central Mechanisms of Botulinum Toxin in Parkinson's Disease: A Systematic Review from Animal Models to Human Evidence
C Cutrona, F Marchet, M Costanzo, MI De Bartolo… - Toxins, 2023 - mdpi.com
… by our review report that the intrastriatal administration of BoNT, … employing
apomorphine-induced rotational behaviour as an … abolished the apomorphine-induced rotational …
apomorphine-induced rotational behaviour as an … abolished the apomorphine-induced rotational …
[HTML][HTML] Antidepressant-like properties of intrastriatal botulinum neurotoxin-a injection in a unilateral 6-ohda rat model of parkinson's disease
V Antipova, C Holzmann, A Hawlitschka, M Witt… - Toxins, 2021 - mdpi.com
… maze test with the rotational behavior induced by apomorphine and … performed a correlation
analysis of drug-induced behaviors. … of the 6-OHDA-induced pathology. In hemi-PD rats, D 1 …
analysis of drug-induced behaviors. … of the 6-OHDA-induced pathology. In hemi-PD rats, D 1 …
[HTML][HTML] Botulinum neurotoxins in central nervous system: An overview from animal models to human therapy
S Luvisetto - Toxins, 2021 - mdpi.com
… different effects on the behavioral responses induced by the long-… intrastriatal injection
of BoNT/A (see [102] for doses) abolished pathologic rotational behavior and induces axonal …
of BoNT/A (see [102] for doses) abolished pathologic rotational behavior and induces axonal …
[HTML][HTML] Olfactory Bulb D2/D3 Receptor Availability after Intrastriatal Botulinum Neurotoxin-A Injection in a Unilateral 6-OHDA Rat Model of Parkinson's Disease
T Alberts, V Antipova, C Holzmann, A Hawlitschka… - Toxins, 2022 - mdpi.com
… can reverse most of the pathological motor symptoms and … and reversed apomorphine-induced
rotational behavior [58]. … that both direct and indirect axonal connections may act as the …
rotational behavior [58]. … that both direct and indirect axonal connections may act as the …
[HTML][HTML] Botulinum toxin A ameliorates neuroinflammation in the MPTP and 6-OHDA-induced Parkinson's disease models
HJ Ham, IJ Yeo, SH Jeon, JH Lim, SS Yoo… - Biomolecules & …, 2022 - ncbi.nlm.nih.gov
… Effects of BoNT-A on behavioral impairments induced by … of BoNT-A on behavioral disorders
induced by MPTP. The rota-… significant differences related to behavioral disorders. However, …
induced by MPTP. The rota-… significant differences related to behavioral disorders. However, …
Interlinking potential therapy with botulinum neurotoxin-A and Parkinson's disease
A Wree, A Hawlitschka, C Holzmann, M Witt… - … and Management in …, 2020 - Elsevier
… nigra pars compacta and axonal degeneration of dopaminergic fibers in … Intrastriatal injections
of botulinum neurotoxin-A in 6-… (D) Amphetamine-induced rotations were slightly but not …
of botulinum neurotoxin-A in 6-… (D) Amphetamine-induced rotations were slightly but not …
[HTML][HTML] Lasting peripheral and central effects of botulinum toxin type A on experimental muscle hypertonia in rats
P Šoštarić, B Vukić, L Tomašić, I Matak - International journal of molecular …, 2022 - mdpi.com
… toxin axonal transport from the injected peripheral site [25,26,27,28,29]. Moreover, peripherally
injected BoNT-A induces … of action relevant only for pathological muscle hyperactivity. In …
injected BoNT-A induces … of action relevant only for pathological muscle hyperactivity. In …
[HTML][HTML] Distribution of Cleaved SNAP-25 in the Rat Brain, following Unilateral Injection of Botulinum Neurotoxin-A into the Striatum
F Schümann, O Schmitt, A Wree… - International Journal of …, 2023 - mdpi.com
… Here, we aimed to determine the spread of intrastriatally injected … The apomorphine-induced
rotation test is based on a … areas after intrastriatal injection but reaches them through axonal …
rotation test is based on a … areas after intrastriatal injection but reaches them through axonal …
The Behavioural Effects and Sept-Hippocampal Cholinergic Activity Changes Caused by Repeated Bont/A Injection on Facial Muscle in Adolescent Mice
X Xu, L Ni, D Sun, H Chen, Q Tang, S Cao… - A Injection on Facial … - papers.ssrn.com
… suggested that toxin can be retrograde axonal transported to the … and neuronal plasticity
induced by altered proprioceptive signals … Intrastriatal injection of botulinum neurotoxin-A is not …
induced by altered proprioceptive signals … Intrastriatal injection of botulinum neurotoxin-A is not …
Parkinson's disease in women: mechanisms underlying sex differences
… It was also observed to abolish the apomorphine-induced rotations through an increase
in … Local intrastriatal administration of BoNTA is known to cause varicosities (large axonal …
in … Local intrastriatal administration of BoNTA is known to cause varicosities (large axonal …