Predicting aggressive multiple sclerosis with intrathecal IgM synthesis among patients with a clinically isolated syndrome
E Monreal, S Sainz de la Maza… - Neurology …, 2021 - AAN Enterprises
… disability milestones, in contrast to OCMB and IgM index. However, LS-OCMB provided a
2-fold significantly higher sensitivity than Reibergram, even if these results are probably …
2-fold significantly higher sensitivity than Reibergram, even if these results are probably …
High levels of cerebrospinal fluid kappa free light chains relate to IgM intrathecal synthesis and might have prognostic implications in relapsing multiple sclerosis
J Castillo-Villalba, S Gil-Perotín… - Frontiers in …, 2022 - frontiersin.org
… tool to OCGBs and as a risk factor for neurological disability and treatment failure. … to
progressive disease and long-term disability in MS (24). Comabella et al. showed a correlation …
progressive disease and long-term disability in MS (24). Comabella et al. showed a correlation …
Prognostic role of intrathecal IgM synthesis in multiple sclerosis: Results from a clinical series
M Fonderico, T Biagioli, L Lanzilao… - Multiple Sclerosis …, 2021 - journals.sagepub.com
… Disability Status Scale, IgG oligoclonal bands and disease-… and infectious diseases of the
central nervous system (CNS), … 13% 21 without any correlation with disability and inflammatory …
central nervous system (CNS), … 13% 21 without any correlation with disability and inflammatory …
Intrathecal IgM synthesis is associated with spinal cord manifestation and neuronal injury in early MS
…, J Kuhle, for the Swiss MS Cohort Study - … of neurology, 2022 - Wiley Online Library
… MS, 8 even when asymptomatic they appear to be the strongest MRI predictor of physical
disability … of Ig subtypes is not evenly and independently distributed and to analyze it in relation …
disability … of Ig subtypes is not evenly and independently distributed and to analyze it in relation …
Intrathecal immunoglobulin M synthesis is an independent biomarker for higher disease activity and severity in multiple sclerosis
…, for the Swiss Multiple Sclerosis Cohort Study - … of neurology, 2021 - Wiley Online Library
… Additionally, we demonstrate that the presence of intrathecal IgM production is associated
with a … In contrast, intrathecal IgM synthesis and its relation to treatment effects have not been …
with a … In contrast, intrathecal IgM synthesis and its relation to treatment effects have not been …
Decoding intrathecal immunoglobulins and B cells in the CNS: their synthesis, function, and regulation: Modulation of immune responses mediated by different B cells …
N Negi, BK Das - International Reviews of Immunology, 2020 - Taylor & Francis
… correlation between intrathecal production of IgM and early onset of MS and reported that
intrathecal production of IgM … of intrathecal IgG synthesis with expanded disability status scale (…
intrathecal production of IgM … of intrathecal IgG synthesis with expanded disability status scale (…
Intrathecal IgM as a prognostic marker in multiple sclerosis
MT Mailand, JL Frederiksen - Molecular diagnosis & therapy, 2020 - Springer
… nervous system (CNS). As the symptoms and course of the … was found to be a negative
predictor of long-term disability … , a moderate negative correlation was found between IgM loc …
predictor of long-term disability … , a moderate negative correlation was found between IgM loc …
Prognostic value of intrathecal IgM synthesis determined by various laboratory methods in patients with early multiple sclerosis-a prospective observational study
K Revendova, D Zeman, P Kusnierova… - Multiple Sclerosis and …, 2022 - Elsevier
… disability in patients after the first demyelinating event of MS. … of Neurology, University
Hospital Ostrava, Czech Republic. … Correlation of individual methods for determining intrathecal …
Hospital Ostrava, Czech Republic. … Correlation of individual methods for determining intrathecal …
Oligoclonal IgM bands in the cerebrospinal fluid of patients with relapsing MS to inform long-term MS disability
R Capuano, I Zubizarreta… - Multiple Sclerosis …, 2021 - journals.sagepub.com
… intrathecal IgM synthesis and CSF NfL levels when measured at the early RMS stage to predict
long-term retinal neuro… inter-eye correlation including sex, age at onset, disease duration, …
long-term retinal neuro… inter-eye correlation including sex, age at onset, disease duration, …
Cerebrospinal fluid IgM levels in association with inflammatory pathways in multiple sclerosis patients
R Magliozzi, V Mazziotti, L Montibeller… - Frontiers in Cellular …, 2020 - frontiersin.org
… stages, being associated in patients with a more disability … the potential correlation between
IgM intrathecal synthesis and … aimed to define quantitatively the intrathecal IgM levels and its …
IgM intrathecal synthesis and … aimed to define quantitatively the intrathecal IgM levels and its …