Effects of the Na+/H+ Ion Exchanger on Susceptibility to COVID-19 and the Course of the Disease

M Cumhur Cure, E Cure - Journal of the Renin-Angiotensin …, 2021 - journals.sagepub.com
… The angiotensin II (Ang II) level is high in chronic diseases such as diabetes, hypertension,
… The Ca 2+ /H + ion antiport activates simultaneously with NHE and pumps Ca 2+ into the cell […

Strong relationship between cholesterol, low-density lipoprotein receptor, Na+/H+ exchanger, and SARS-COV-2: this association may be the cause of death in the …

E Cure, M Cumhur Cure - Lipids in Health and Disease, 2021 - Springer
Na + /H + Exchanger (NHE) is an important antiport that … falls, NHE is activated and pumps
H + ions outward. However… angiotensin II (Ang II) due to angiotensin-converting enzyme-…

[HTML][HTML] The Na+/H+ exchanger 3 in the intestines and the proximal tubule of the kidney: localization, physiological function, and key roles in angiotensin II-induced …

SM Nwia, XC Li, APO Leite, R Hassan… - Frontiers in …, 2022 - frontiersin.org
… of the most important Na + /H + antiporters in the small intestines … , there were no differences
in plasma pH, plasma ions or … Conversely, activation of AT 2 receptors by Ang II appears to …

[PDF][PDF] Strong relationship between cholesterol, low-density lipoprotein receptor, Na/H exchanger, and SARS-COV-2: this association may be the cause of death in the …

E Cure, MC Cure - 2021 - lipidworld.biomedcentral.com
Na+/H+ Exchanger (NHE) is an important antiport that keeps … falls, NHE is activated and
pumps H+ ions outward. However… Angiotensin II upregulates LDL receptor-related protein (LRP1…

… Angiotensin II Stimulation of Sodium Transporter Expression in Proximal Tubule Cells via AT1 (AT1a) Receptor-Mediated, MAP Kinases ERK1/2- and NF-кB …

X Li, J Zhuo - Cells, 2023 - mdpi.com
… ), are mediated by extracellular Ang II activating its cell … of the kidney expresses abundant
Na + antiporters and Na + -… the H + ion into the tubular lumen in exchange for the entry of Na + …

Megalin is involved in angiotensinogen-induced, angiotensin II-mediated ERK1/2 signaling to activate Na+-H+ exchanger 3 in proximal tubules

…, S Kuwahara, H Kabasawa, H Aoki… - Journal of …, 2023 - journals.lww.com
II and its recovery. In the parallel reaction monitoring (PRM) workflow, a target Ang peptide of
a predefined m/z range (a precursor ion) … to produce several product ions, of which their m/z …

Prolonged NHE activation may be both cause and outcome of cytokine release syndrome in COVID-19

MC Cure, E Cure - Current Pharmaceutical Design, 2022 - ingentaconnect.com
… NHE activation in COVID-19 may cause a decrease in intracellular pH through H+ ion ac…
the precursor peptide of angiotensin II, and angiotensin I and angiotensin II are formed from …

Angiotensin II and AT1a Receptors in the Proximal Tubules of the Kidney: New Roles in Blood Pressure Control and Hypertension

APO Leite, XC Li, SM Nwia, R Hassan… - International Journal of …, 2022 - mdpi.com
… , intracellular Na + ions are returned to the blood via the Na + … ,76], also stimulate proximal
tubule Na + reabsorption, in part, by … II and its major metabolite Ang III reportedly activate AT 2

Impact of Impaired Kidney Function on Arrhythmia-Promoting Cardiac Ion Channel Regulation

F Sinha, F Schweda, LS Maier, S Wagner - International Journal of …, 2023 - mdpi.com
… (ECC) is based on the activation and inactivation of different ion channels, which causes
a … drug target in their treatment. Angiotensin II is known to regulate several ion channels in …

[HTML][HTML] Severe acute respiratory syndrome coronavirus 2 may cause liver injury via Na+/H+ exchanger

MC Cure, E Cure - World Journal of Virology, 2023 - ncbi.nlm.nih.gov
… factor-alpha and angiotensin II decrease NHE3 activity in the … There are many ion pumps in
plasma membranes. They … physiological conditions, its continuous activation causes serious …