[HTML][HTML] The ferroptosis and iron-metabolism signature robustly predicts clinical diagnosis, prognosis and immune microenvironment for hepatocellular carcinoma
B Tang, J Zhu, J Li, K Fan, Y Gao, S Cheng… - Cell Communication and …, 2020 - Springer
… As it was determined that erastin inhibited the proliferation and progression of HCC, we
explored the possible molecular mechanism by which erastin achieves antitumor effects. In the …
explored the possible molecular mechanism by which erastin achieves antitumor effects. In the …
Crosstalk between macrophages, T cells, and iron metabolism in tumor microenvironment
… proving the role of iron in tumor development, metastasis, and TME modification [13, 14].
In this review, we briefly introduce the pathophysiology of iron metabolism and leukocytes, …
In this review, we briefly introduce the pathophysiology of iron metabolism and leukocytes, …
The detrimental effect of iron on OA chondrocytes: Importance of pro‐inflammatory cytokines induced iron influx and oxidative stress
X Jing, T Du, T Li, X Yang, G Wang… - … and molecular …, 2021 - Wiley Online Library
… the roles of iron homeostasis and iron overload mediated … chondrocytes iron homeostasis
via upregulating iron influx … molecular mechanisms of OA still remain poorly understood. …
via upregulating iron influx … molecular mechanisms of OA still remain poorly understood. …
[HTML][HTML] ACSL4 as a potential target and biomarker for anticancer: from molecular mechanisms to clinical therapeutics
J Hou, C Jiang, X Wen, C Li, S Xiong, T Yue… - Frontiers in …, 2022 - frontiersin.org
… in some genes that regulate iron homeostasis and lipid peroxidation metabolism. In the … )
exhaustion, cystine deprivation and abnormal iron metabolism. As for anti-ferroptosis pathway, …
exhaustion, cystine deprivation and abnormal iron metabolism. As for anti-ferroptosis pathway, …
Analyzing the mechanisms of iron oxide nanoparticles interactions with cells: A road from failure to success in clinical applications
… molecular mechanisms of IONPs-cell interactions will provide a basement to increase the
likelihood for clinical … Indeed, normal iron homeostasis is mediated through iron absorption, …
likelihood for clinical … Indeed, normal iron homeostasis is mediated through iron absorption, …
[HTML][HTML] Mechanism of ferroptosis and its relationships with other types of programmed cell death: insights for potential interventions after intracerebral hemorrhage
SY Zhou, GZ Cui, XL Yan, X Wang, Y Qu… - Frontiers in …, 2020 - frontiersin.org
… Here, we focus on the potential targets, including iron metabolism, GSH biosynthesis, and …
molecules are known to regulate ferroptosis by directly or indirectly targeting iron metabolism, …
molecules are known to regulate ferroptosis by directly or indirectly targeting iron metabolism, …
The role of iron repletion in adult iron deficiency anemia and other diseases
B Elstrott, L Khan, S Olson… - European journal of …, 2020 - Wiley Online Library
… Iron absorption occurs in the duodenum and is regulated by the divalent metal transporter (…
blocks iron absorption into the circulation via ferroportin degradation and inhibits iron release …
blocks iron absorption into the circulation via ferroportin degradation and inhibits iron release …
Mechanisms of mitochondrial iron-sulfur protein biogenesis
R Lill, SA Freibert - Annual review of biochemistry, 2020 - annualreviews.org
… molecular mechanisms underlying the ISC protein–mediated maturation of mitochondrial
Fe/… /S cluster–dependent processes encompass the regulation of cellular iron homeostasis by …
Fe/… /S cluster–dependent processes encompass the regulation of cellular iron homeostasis by …
[HTML][HTML] Regulation of tissue iron homeostasis: the macrophage “ferrostat”
… iron homeostasis, supplying or sequestering iron as needed for erythropoiesis or bacteriostasis,
respectively. Indeed, recycling of iron … the molecular mechanisms that govern iron cycling…
respectively. Indeed, recycling of iron … the molecular mechanisms that govern iron cycling…
[HTML][HTML] Effects of maternal iron status on placental and fetal iron homeostasis
V Sangkhae, AL Fisher, S Wong… - … Journal of clinical …, 2021 - Am Soc Clin Investig
… The authors identified molecular mechanisms that limit placental ability to upregulate … of
iron deficiency of the materno-fetal unit. We present evidence that placental iron homeostasis is …
iron deficiency of the materno-fetal unit. We present evidence that placental iron homeostasis is …