… The existing evidence suggests no added survival benefit … Overall, a random-effects analysis
of β-lactam/aminoglycoside … or did not receive a short course of gentamicin administered as …

… demonstrate beneficial effects of a short-course of aminoglycosides added to β-lactam
antibiotics on 30-day mortality … and uncertainty about its benefits, a randomized trial is warranted. …

… Whether a short course of aminoglycosides, that is often … addition to the obvious complexity
of conducting clinical trials… with acute pyelonephritis: a randomized trial of ampicillin versus …

… A random intercept linear mixed model was used to evaluate … the addition of aminoglycosides
to β-lactam antibiotics in the … concluding that the addition of an aminoglycoside did not …

… Simultaneously, extending the dose intervals of aminoglycosides might … Although randomized
controlled trials on TDM and … In addition, TDM helps monitor PK target attainment and …

… Nevertheless, most of the randomized clinical trials (RCT) … once-daily dosing regimen and
in a short course (13, 23). As reported in … In addition to choosing the optimal empirical β-lactam …

… In trials spanning 35 years, neither the addition of an aminoglycoside for S aureus endocarditis
18 nor of rifampicin for S aureus bacteremia 19 resulted in improved clinical outcomes; …

… of data in treating CRE infections in randomized controlled trials, these data, taken with in …
to the antibiotic and during active treatment. Aminoglycosides have been utilized as add-on …

… Of those we tested the efficacy of combinations of 2 common β-lactam antibiotics … Added
value of this study … In this study, we aimed to characterize the antibiotic interaction profiles in vitro …

… Although monitoring of aminoglycoside concentrations to … of this dosing strategy adds
additional emphasis to obtaining … Randomized controlled trials (RCTs) evaluating TDM of β-…