Coordinated interactions between endothelial cells and macrophages in the islet microenvironment promote β cell regeneration
DC Saunders, KI Aamodt, TM Richardson… - NPJ Regenerative …, 2021 - nature.com
… vascular endothelial growth factor-A (VEGF-A) regulates islet … of growth factors—whose
bioavailability is likely modulated … with increased integrin signaling promotes activation of pro-…
bioavailability is likely modulated … with increased integrin signaling promotes activation of pro-…
Islet vascularization is regulated by primary endothelial cilia via VEGF-A-dependent signaling
Y Xiong, MJ Scerbo, A Seelig, F Volta, N O'Brien… - Elife, 2020 - elifesciences.org
… in islet vascularization is vascular endothelial growth factor-A (VEGF-A)/VEGF receptor 2 (VEGFR2)
dependent signaling. VEGF… Islet vascularization is in part modulated by changing the …
dependent signaling. VEGF… Islet vascularization is in part modulated by changing the …
[PDF][PDF] β-cell Exhaustion and Islet Microenviron-ment: The Role of Local Vascular Network
PRV Local - Revista Portuguesa de Diabetes, 2024 - revportdiabetes.com
… islet cells and their microenvironment, highlighting the … islets that may modulate neural
signaling and influence islet … of the angiogenic vascular endothelial growth factor A by endocrine β…
signaling and influence islet … of the angiogenic vascular endothelial growth factor A by endocrine β…
Beta cell dysfunction in diabetes: the islet microenvironment as an unusual suspect
… of the islet from the point of view of the islet microenvironment and, using … beta cells, illustrate
how the microenvironment and beta cells depend on … Vascular endothelial growth factor-A …
how the microenvironment and beta cells depend on … Vascular endothelial growth factor-A …
Diet-induced obesity results in endothelial cell desensitization to VEGF-A and permanent islet vascular dysfunction
Y Xiong, A Dicker, M Visa, E Ilegems, PO Berggren - bioRxiv, 2023 - biorxiv.org
… cell growth factor A (VEGF-A) in a mouse model of diet-… membrane of islet vascular endothelial
cells, as identified by the … VEGF-A/VEGFR2 signaling is a key modulator of islet vascular …
cells, as identified by the … VEGF-A/VEGFR2 signaling is a key modulator of islet vascular …
[HTML][HTML] Vascular and immune interactions in islets transplantation and 3D islet models
A Migliorini, MC Nostro - Current Opinion in Genetics & Development, 2024 - Elsevier
… factors, including vascular endothelial growth factor (VEGF), … and controlling the islet
microenvironment, current islet-on-a-… study vascular formation and pharmacological modulation of …
microenvironment, current islet-on-a-… study vascular formation and pharmacological modulation of …
The roles of cell-cell and organ-organ crosstalk in the type 2 diabetes mellitus associated inflammatory microenvironment
D Gao, J Jiao, Z Wang, X Huang, X Ni, S Fang… - Cytokine & Growth …, 2022 - Elsevier
… cells and endothelial cells, secrete multiple cytokines, such as CSF-1, TGF-β1 and vascular
endothelial growth factor-A (VEGFA), promoting M2-like islet macrophage polarization [27], […
endothelial growth factor-A (VEGFA), promoting M2-like islet macrophage polarization [27], […
… and opportunities in the islet transplantation microenvironment: a comprehensive summary of inflammatory cytokine, immune cells, and vascular endothelial cells
Q Chen, L Liu, X Zhao, J Liang, S Li - Frontiers in Immunology, 2023 - frontiersin.org
… However, an excess of vascular endothelial growth factor (VEGF) is not universally … possible
to implement strategies to modulate the islet microenvironment in ways not currently feasible …
to implement strategies to modulate the islet microenvironment in ways not currently feasible …
Metformin attenuates high glucose-induced injury in islet microvascular endothelial cells
W Zou, B Liu, Y Wang, F Shi, S Pang - Bioengineered, 2022 - Taylor & Francis
… of vascular endothelial growth factor-A (VEGF-A) and … caused by high glucose (HG)
levels by modulating FXR. … of the local islet microenvironment by VEGF-A signaling plays an …
levels by modulating FXR. … of the local islet microenvironment by VEGF-A signaling plays an …
Bone marrow-derived mesenchymal stem cells improve rat islet graft revascularization by upregulating ISL1
Y Wang, JW Wang, Y Li, XH Tian, XS Feng… - Stem Cells, 2021 - academic.oup.com
… protein as a potential modulator in BMSCs-mediated revascularization of islet grafts. We …
in ISL1 and vascular endothelial growth factor A (VEGFA) expression in both islets and the INS-…
in ISL1 and vascular endothelial growth factor A (VEGFA) expression in both islets and the INS-…