Mesenchymal stem cell-derived extracellular vesicles: a novel cell-free therapy

M Jafarinia, F Alsahebfosoul, H Salehi… - Immunological …, 2020 - Taylor & Francis
stem cells (MSCs) can be easily isolated from different sources and differentiate into various
cell … migration of kidney-derived epithelial cells in vitro and improves the survival of tubular …

[HTML][HTML] Extracellular vesicles derived from different tissues attenuate cardiac dysfunction in murine MI models

X Liu, S Shi, X Geng, E Wang, Q Meng, M Li, F Lin… - Biology Direct, 2023 - Springer
… EVs (cEVs) and kidney-derived EVs (nEVs) were isolated and intramyocardially injected into
… from different types of cells, including mesenchymal stem cells (MSCs) [12, 13], embryonic …

[HTML][HTML] Biodistribution of mesenchymal stromal cell-derived extracellular vesicles administered during acute lung injury

A Tieu, DJ Stewart, D Chwastek, C Lansdell… - Stem Cell Research & …, 2023 - Springer
… One of the first studies in non-human primates found the liver and spleen to be the major
site of uptake for EVs generated by a human embryonic kidney-derived cell line (detected up to …

[HTML][HTML] Novel cell lines derived from Chinese hamster kidney tissue

Y Kawabe, M Kamihira - PloS one, 2022 - journals.plos.org
cells are applicable to the fields of biotechnology and biomedical science by utilizing their
characteristics as kidney-derived cells… CHK-Q cells might be transformed from renal stem cells. …

[HTML][HTML] Mesenchymal stem cell therapy in acute kidney injury (AKI): review and perspectives

C Sávio-Silva, PE Soinski-Sousa… - Revista da Associação …, 2020 - SciELO Brasil
Kidney-derived c-kit(+) progenitor/stem cells contribute to podocyte recovery in a model
of acute proteinuria. Sci Rep 2018; 8:14723-. In addition to paracrine effects, c-Kit …

Regenerative treatments for kidney diseases: The closest and fastest strategies to solving related medical and economic problems

K Osafune - Artificial Organs, 2021 - Wiley Online Library
… Indeed, multiple clinical trials using MSCs, bone marrow stem cells, and kidney-derived
cells have already been carried out. This review summarizes the current status and future …

[HTML][HTML] Mesenchymal stem cell-derived exosomes as an emerging paradigm for regenerative therapy and nano-medicine: A comprehensive review

B Panda, Y Sharma, S Gupta, S Mohanty - Life, 2021 - mdpi.com
… In line with this observation, EVs released from kidney-derived MSCs preincubated with
RNase failed to ameliorate TGF-β1-induced peritubular capillary rarefaction and …

Clonal Hematopoiesis of Indeterminate Potential Associates with Severe AKI: SA-PO180

J Chen, C Vlasschaert… - Journal of the …, 2023 - journals.lww.com
… is the clonal expansion of hematopoietic stem cells due to somatic mutations … Kidney-derived
uromodulin is protective in a mouse model of sepsis, where it promotes proper myeloid cell

[HTML][HTML] Renal inflamm-aging provokes intra-graft inflammation following experimental kidney transplantation

A He, A Sarwar, LML Thole, J Siegle, A Sattler… - American Journal of …, 2022 - Elsevier
… T cells, whereas regulatory T cells were reduced. Aged kidney-derived CD8 + T cells produced
… regenerative capacity of stem cells and their progeny accelerates cellular senescence. …

Mesenchymal stem cell‐derived extracellular vesicles in treatment against renal fibrosis

J Wang, J Cui, S Yu, S Xia - Clinical and Translational …, 2023 - Wiley Online Library
… endothelial cells. Choi et al. reported that kidney-derived MSC-EVs led to increased density
and perfusion of renal capillaries through the downregulation of hypoxia inducible factor-1α. …