[HTML][HTML] Isoorientin attenuates cisplatin-induced nephrotoxicity through the inhibition of oxidative stress and apoptosis via activating the SIRT1/SIRT6/Nrf-2 pathway
X Fan, W Wei, J Huang, X Liu, X Ci - Frontiers in Pharmacology, 2020 - frontiersin.org
… inflammatory activities and antioxidant activities (Anilkumar et al., 2017). And, we found that
… ameliorates APAP-induced hepatotoxicity via the activation of the Nrf2 antioxidative pathway …
… ameliorates APAP-induced hepatotoxicity via the activation of the Nrf2 antioxidative pathway …
Isoorientin exerts a protective effect against 6-OHDA-induced neurotoxicity by activating the AMPK/AKT/Nrf2 signalling pathway
L Ma, B Zhang, J Liu, C Qiao, Y Liu, S Li, H Lv - Food & function, 2020 - pubs.rsc.org
… whether IOT could ameliorate neurotoxicity and the … Nrf2 signalling pathway, as an
antioxidant signalling pathway, plays a key role in modulating the expression of many antioxidant …
antioxidant signalling pathway, plays a key role in modulating the expression of many antioxidant …
[HTML][HTML] Smilax china L. Polysaccharide Alleviates Oxidative Stress and Protects From Acetaminophen-Induced Hepatotoxicity via Activating the Nrf2-ARE Pathway
K Wang, L Yang, J Zhou, X Pan, Z He, J Liu… - Frontiers in …, 2022 - frontiersin.org
… the APAP-induced increases in serum AST, ALT and LDH activity and ameliorated hepatocyte
… , thereby enhancing the antioxidant defense system to prevent APAP-induced oxidative …
… , thereby enhancing the antioxidant defense system to prevent APAP-induced oxidative …
[HTML][HTML] Xanthohumol protect against acetaminophen-induced hepatotoxicity via Nrf2 activation through the AMPK/Akt/GSK3β pathway
L Zhu, X Fan, C Cao, K Li, W Hou, X Ci - Biomedicine & Pharmacotherapy, 2023 - Elsevier
… In vivo, xanthohumol significantly ameliorated acetaminophen-… to activate Nrf2, Nrf2-mediated
the expression of antioxidant … that Xn inhibited APAP-induced liver toxicity in WT mice but …
the expression of antioxidant … that Xn inhibited APAP-induced liver toxicity in WT mice but …
[HTML][HTML] Naringin regulates mitochondrial dynamics to protect against acetaminophen-induced hepatotoxicity by activating the AMPK/Nrf2 signaling pathway in vitro
Q Wu, P Yu, Y Bi, Z Li, W Guo, Y Chen… - Brazilian Journal of …, 2022 - SciELO Brasil
… Isoorientin ameliorates APAP-induced hepatotoxicity via activation Nrf2 antioxidative pathway:
… II detoxification gene expression via activation of the PI3K and PKC signaling pathways. J …
… II detoxification gene expression via activation of the PI3K and PKC signaling pathways. J …
Isoorientin Alleviates Inflammatory Bowel Disease by Inhibiting NLRP3 Inflammasome Activation through Nrf2/NQO1 Pathway.
Q Cheng, X Yu, R Zhang… - Current Topics in …, 2020 - search.ebscohost.com
… A previous study found ISO to affect nephrotoxicity via activating the SIRT1/ Nrf2 pathway (…
Isoorientin ameliorates APAPinduced hepatotoxicity via activation Nrf2 antioxidative pathway: …
Isoorientin ameliorates APAPinduced hepatotoxicity via activation Nrf2 antioxidative pathway: …
Isoorientin reverses lung cancer drug resistance by promoting ferroptosis via the SIRT6/Nrf2/GPX4 signaling pathway
S Feng, Y Li, H Huang, H Huang, Y Duan… - European Journal of …, 2023 - Elsevier
… In this study, the combination of isoorientin (IO) and DDP … The Nrf2 protein is a pivotal factor
in the cellular antioxidant … endogenous antioxidant pathways and controlling the antioxidant …
in the cellular antioxidant … endogenous antioxidant pathways and controlling the antioxidant …
… alleviates acetaminophen-induced acute liver injury through the activation of Keap1/Nrf2-mediated lipid peroxidation defense via the AMPK/SIRT3 signaling pathway
L Zhao, X Zhang, Z Chen, Y Lai, J Xu, R Zhou, P Ma… - Food & Function, 2024 - pubs.rsc.org
… defense via activation of the AMPK/SIRT3 signaling pathway. … of natural antioxidants in
treating APAP-induced ALI. … against APAP-induced ALI by activating the Keap1/Nrf2 pathway-…
treating APAP-induced ALI. … against APAP-induced ALI by activating the Keap1/Nrf2 pathway-…
… from Penthorum chinense Pursh suppresses HMGB1/TLR4/NF-κB signaling and NLRP3 inflammasome activation in acetaminophen-induced hepatotoxicity
YC Du, L Lai, H Zhang, FR Zhong, HL Cheng… - Food & function, 2020 - pubs.rsc.org
… antioxidant activity. In this study, we explored the protective effect and novel mechanism of
KA against APAP-induced hepatotoxicity. … via activating the HMGB1/TLR4 pathway in models …
KA against APAP-induced hepatotoxicity. … via activating the HMGB1/TLR4 pathway in models …
[PDF][PDF] Bioactive phytoconstituents with hepatoprotective potential: a review.
… Isoorientin ameliorated APAP-induced hepatotoxicity by activating Nrf2 via the AMPK/Akt/GSK3b
pathway… with exogenic antioxidant effect and adequate hepatotoxic potential data …
pathway… with exogenic antioxidant effect and adequate hepatotoxic potential data …