Construction of Feedforward Multilayer Perceptron Model for Diagnosing Leishmaniasis Using Transcriptome Datasets and Cognitive Computing
MA Sundaramahalingam, R Kabra, S Singh - Machine Learning and …, 2022 - Springer
… Leishmania is a protozoan parasite responsible for … types of leishmaniasis: cutaneous
leishmaniasis, mucocutaneous … We used 80% of datasets as training data and 20% as the testing …
leishmaniasis, mucocutaneous … We used 80% of datasets as training data and 20% as the testing …
Use of genome editing in human phagocytic cells to elucidate the role of the NLRP3 inflammasome in L. major infection
K Volkmar - 2023 - openscience.ub.uni-mainz.de
… visceral leishmaniasis some patients suffer from post-kala-… Among the Old-World species of
Leishmania L. major is one of … The course of cutaneous leishmaniasis is well understood and …
Leishmania L. major is one of … The course of cutaneous leishmaniasis is well understood and …
[PDF][PDF] IMMUNOBIOLOGY OF LEISHMANIASIS
… infection, the other Leishmania species that cause visceral … susceptibility, for visceral
leishmaniasis we are still unable to … response that increased with the course of infection (Figure …
leishmaniasis we are still unable to … response that increased with the course of infection (Figure …
Metabolite Biomarkers of Leishmania Antimony Resistance
… Notably, the VL can be lethal in the absence of treatment [4]. … responsible for visceral and
cutaneous leishmaniasis. Hence, it is … per strain in order to synchronize the cell cultures and to …
cutaneous leishmaniasis. Hence, it is … per strain in order to synchronize the cell cultures and to …
Opportunities and Difficulties in the Repurposing of HDAC Inhibitors as Antiparasitic Agents
TK Mohapatra, RR Nayak, A Ganeshpurkar… - Drugs and Drug …, 2024 - mdpi.com
… alterations in the eukaryotes synchronize the regulation of … Still, no one class-I/II HDAC
species of Leishmania has been … , used to treat visceral Leishmaniasis. Antiparasitic activity …
species of Leishmania has been … , used to treat visceral Leishmaniasis. Antiparasitic activity …
Of Drugs and Trypanosomatids: New Tools and Knowledge to Reduce Bottlenecks in Drug Discovery
B Arijit, A Corbeil, RL Monte Neto, C Fernandez-Prada - 2020 - arca.fiocruz.br
… good model for VL with synchronous infection in the liver and spleen … for Leishmania, as
relapsing conditions like post-kala-azar … for visceral leishmaniasis and leishmaniasis recidivans …
relapsing conditions like post-kala-azar … for visceral leishmaniasis and leishmaniasis recidivans …
[PDF][PDF] Genome Plasticity in Cultured Leishmania donovani: Comparison of Early and Late Passages
… causes visceral leishmaniasis or kala-azar, which is a fatal … A pseudo gene of MFS class of
proteins present in HTI4 is … the late passage promastigotes in sync with earlier observation in L…
proteins present in HTI4 is … the late passage promastigotes in sync with earlier observation in L…
Targeting Trypanothione Metabolism in Trypanosomatids
MC González-Montero, J Andrés-Rodríguez… - Molecules, 2024 - mdpi.com
… Different Leishmania species exhibit distinct geographical … infantum is associated with
visceral leishmaniasis in the … , oxabicyclonanones were identified as a new class of inhibitors of …
visceral leishmaniasis in the … , oxabicyclonanones were identified as a new class of inhibitors of …
Exploring N-myristoyltransferase as a promising drug target against parasitic neglected tropical diseases
IJ dos Santos Nascimento, MAT Cavalcanti… - European Journal of …, 2023 - Elsevier
… More than 20 species of Leishmania are known, which are … forms: Cutaneous Leishmaniasis
(CL); Visceral Leishmaniasis (… is fatal in most cases in infection of African baby [66,70]. The …
(CL); Visceral Leishmaniasis (… is fatal in most cases in infection of African baby [66,70]. The …
Temperate zone plant natural products—a novel resource for activity against tropical parasitic diseases
H Hameed, EFB King, K Doleckova, B Bartholomew… - Pharmaceuticals, 2021 - mdpi.com
… Trypanosomatidae family (Leishmania and Trypanosoma species) … severe form is visceral
leishmaniasis (VL) or kala-azar, in … When required, cultures were synchronised to ring stages …
leishmaniasis (VL) or kala-azar, in … When required, cultures were synchronised to ring stages …