[HTML][HTML] Effect of thymoquinone on acetic acid-induced visceral nociception in rats: role of central cannabinoid and α2-adrenergic receptors

S Naderi, E Tamaddonfard, S Nafisi… - Veterinary Research …, 2024 - ncbi.nlm.nih.gov
… mg kg -1 ; PO)-induced anti-nociception. Locomotor activity was not … Under anesthesia induced
by IP injection of ketamine (… uses both peripheral and central L-arginine/nitric oxide/cyclic

[HTML][HTML] Promising Effects of Casearins in Tumor-Bearing Mice and Antinociceptive Action against Oncologic Pain: Molecular Docking and In Vivo Findings

JN Silva, JIA Beserra Filho, BT Acha, FRC Almeida… - Pharmaceuticals, 2024 - mdpi.com
… When formed, it activates the enzyme guanylate cyclase, … targets, including cyclic guanosine
monophosphate (cGMP)-… On the 16th day, the animals were anesthetized with ketamine (…

[HTML][HTML] Methanol Extract of Dicranopteris linearis Leaves Attenuate Pain via the Modulation of Opioid/NO-Mediated Pathway

ZA Zakaria, RAJ Roosli, NH Marmaya, MH Omar… - Biomolecules, 2020 - mdpi.com
… of antinociception involved using various standardized rat or … , NO induces pain while at low
dose NO triggers antinociceptive … , MEDL exerts antinociceptive activity at the peripheral and …

[HTML][HTML] The effect of different anaesthetics on echocardiographic evaluation of diastolic dysfunction in a heart failure with preserved ejection fraction model

I Cuijpers, P Carai, P Mendes-Ferreira… - Scientific Reports, 2020 - nature.com
… and obese ZSF1 rats anaesthetised with ketamine/xylazine (… cardiac intracellular cyclic
adenosine monophosphate (cAMP)… , activation of L-arginine/nitric oxide (NO)/cyclic guanosine-…

[HTML][HTML] Cardamonin modulates neuropathic pain through the possible involvement of serotonergic 5-HT1A receptor pathway in CCI-induced neuropathic pain mice …

NK Kaswan, NAB Mohammed Izham… - Molecules, 2021 - mdpi.com
peripheral nervous system can modulate the antinociceptive … /o protein in which the activation
of these receptors were able … reduce the cyclic adenosine monophosphate cAMP level, …

Synergistic antiallodynic and antihyperalgesic interaction between L-DOPA and celecoxib in parkinsonian rats is mediated by NO–cGMP–ATP-sensitive K+ channel

Y Aguirre-Vidal, C Rodríguez-Ramos… - European journal of …, 2020 - Elsevier
… systematically the antinociceptive effect induced by L-DOPA. … anaesthetized by intraperitoneal
injection of Ketamine (45 mg/kg… the formation of cyclic guanosine monophosphate (cGMP). …

Yueju-Ganmaidazao Decoction confers rapid antidepressant-like effects and the involvement of suppression of NMDA/NO/cGMP signaling

H Zhang, Y Sun, S Qian, R Ge, X Guo, Q Shen… - Journal of …, 2020 - Elsevier
… Lately, ketamine's enantiomer esketamine has been approved by … NMDA receptor activation
stimulates generation of nitric … failure were significantly increased in the LH mice. Similar to …

Antidepressant-Like Activity of Solvent Fractions of the Root Bark of Carissa spinarum Linn. (Apocynaceae) in Rodents Involves Multiple Signaling Pathways

HS Ali, E Engidawork - Journal of Experimental Pharmacology, 2022 - Taylor & Francis
… of the central and peripheral squares were tracked and … animal was immediately anesthetized
with ketamine (80 mg/kg, … levels as a result of activating the major neuroendocrine stress …

… of gingerols-and shogaols-enriched ginger root extract attenuate pain-associated behaviors while modulating gut microbiota and metabolites in rats with spinal nerve …

CL Shen, R Wang, G Ji, MM Elmassry… - The Journal of nutritional …, 2022 - Elsevier
… Ginger elicits antinociceptive properties and intensifies morphine-induced analgesia during
… the activation of 5-HT 1A/1B/1D/5A receptors and the NO-cyclic guanosine monophosphate-…

Comparison of Ketamine-Dexmedetomidine Combination with Fentanyl-Dexmedetomidine Combination for Procedural Sedoanalgesia during CT-Guided …

SB Shah, A Pahade, N Gupta… - … of Anesthesia and …, 2023 - publish.kne-publishing.com
antinociceptive effects of ketamine like nitric oxide synthesis [11] mu-opioid … Ketamine activates
the L-arginine/Nitric oxide/cyclicantinociception in rats. Anesth Analg. 2011; 113:1254-9. …