Ketogenic Diet, Circadian Rhythm and Aging

A Jagota, SA Sharma - Nutrition, Food and Diet in Ageing and Longevity, 2021 - Springer
… population of neuronal circadian oscillators perceives the … in turn can increase intestinal
absorption of nutrients through … Fasting induces ketogenic genes under regulation of mTOR–…

Temporal response to bioenergetic stress in adipose tissue and skeletal muscle

L Pendergrast - 2024 - openarchive.ki.se
… fatty acids and expression of thermogenic and angiogenic … We observed that core clock
genes Neuronal PAS domain … of circadian function in the regulation of skeletal muscle lipid …

A ketogenic diet containing medium-chain triglycerides reduces REM sleep duration without significant influence on mouse circadian phenotypes

H Zhuang, Y Fujikura, N Ohkura… - Food Research …, 2023 - Elsevier
ketone bodies without inducing carbohydrate starvation on … Pdk4 and Ucp3 expression in
skeletal muscle during the light … KD might directly influence the central nervous system via

Dietary factors in circadian rhythm modulation and their impact on metabolic diseases: a state of the science review

M Dalvi, S Medithi - Biological Rhythm Research, 2024 - Taylor & Francis
… The Ketogenic diet (KD) can have an impact on circadian … In KD-fed mice, Slc25a25,
associated with thermogenesis, shows … ) expression in muscle, and is activated through a neural

Molecular regulation of brain metabolism underlying circadian epilepsy

F Chan, J Liu - Epilepsia, 2021 - Wiley Online Library
Ketogenic diet induces expression of the muscle circadian gene Slc25a25 via neural pathway
that might be involved in muscle thermogenesis. Sci Rep. 2017;7:2885. …

A low-carbohydrate ketogenic diet and treadmill training enhanced fatty acid oxidation capacity but did not enhance maximal exercise capacity in mice

S Ma, J Yang, T Tominaga, C Liu, K Suzuki - Nutrients, 2021 - mdpi.com
… us to eat in compliance with our circadian clock [4]. … induced Slc25a25, an ATP carrier in
the inner mitochondria membrane that is partially responsible for thermogenesis in muscle [47]. …

Chronically skipping breakfast impairs hippocampal memory-related gene expression and memory function accompanied by reduced wakefulness and body …

H Okauchi, S Higo-Yamamoto, T Sowa, H Oike… - Biochemical and …, 2020 - Elsevier
… We also examined the effects of SB on circadian rhythms of … We assessed thermogenic
gene expression in BAT and the … in the SB-induced decrease in CBT, because Slc25a25

Uncoupling of sarcoendoplasmic reticulum calcium ATPase pump activity by sarcolipin as the basis for muscle non-shivering thermogenesis

NC Bal, M Periasamy - Philosophical Transactions of the …, 2020 - royalsocietypublishing.org
… that ketogenic diet might recruit muscle thermogenesis using SLN-mediated pathways [83]. …
demand in the muscle by inducing futile ATP hydrolysis by SERCA, it can also increase …

Ketogenic nutritional therapy (KeNuT)—a multi-step dietary model with meal replacements for the management of obesity and its related metabolic disorders: a …

L Barrea, M Caprio, E Camajani, L Verde… - Journal of …, 2024 - Springer
Ketogenic diets induce a metabolic condition called “… by increasing the expression of
thermogenic genes, a biological … -A, which has been shown to positively affect circadian rhythm …

Ketogenic Diet Affects Sleep Architecture in C57BL/6J Wild Type and Fragile X Mice

PR Westmark, AK Gholston, TJ Swietlik… - International Journal of …, 2023 - mdpi.com
… Treatment with a ketogenic diet flattened diurnal sleep … for weight loss and is being tested
in numerous neurological models [… mice suggests that the ketogenic diet may not be beneficial …