A large-scale multicenter retrospective study on nephrotoxicity associated with empiric broad-spectrum antibiotics in critically ill patients
… critically ill patients in the ICU and used a more stringent definition of AKI, defined as Kidney
Disease: … ORs and 95% CIs were calculated to assess the risk of the primary and secondary …
Disease: … ORs and 95% CIs were calculated to assess the risk of the primary and secondary …
Critically Ill Health Care-Associated Urinary Tract Infection: Broad vs. Narrow Antibiotics in the Emergency Department Have Similar Outcomes
KJ Kooda, M Rudis, K Mara, C Clements… - The Journal of …, 2021 - Elsevier
… empiric therapy selection and secondary outcomes, including … ESBL coverage in all critically
ill patients presenting with HCA … Empiric broad-spectrum coverage did not affect outcome in …
ill patients presenting with HCA … Empiric broad-spectrum coverage did not affect outcome in …
Bloodstream infections in critically ill patients: an expert statement
… with systemic signs of infection and may be either secondary … linked with an increased
hazard of acute renal failure at the … the broad-spectrum antimicrobial that was initially started. …
hazard of acute renal failure at the … the broad-spectrum antimicrobial that was initially started. …
Ensuring target concentrations of antibiotics in critically ill patients through dose adjustment
J Gorham, FS Taccone, M Hites - Expert Opinion on Drug …, 2022 - Taylor & Francis
… disorders, either secondary … renal clearance is challenging due to the fact that we have
to take into account non-CRRT CL (renal clearance due to residual renal function plus non-renal …
to take into account non-CRRT CL (renal clearance due to residual renal function plus non-renal …
Risk of acute kidney injury associated with anti-pseudomonal and anti-MRSA antibiotic strategies in critically ill patients
JM Côté, M Desjardins, JF Cailhier, PT Murray… - PLoS …, 2022 - journals.plos.org
… exposure of various broad-spectrum antibiotic regimens with … these findings resulting from
secondary analyses, as many … kidney monitoring, including markers of kidney damage and …
secondary analyses, as many … kidney monitoring, including markers of kidney damage and …
Failure of target attainment of beta-lactam antibiotics in critically ill patients and associated risk factors: a two-center prospective study (EXPAT)
… ) as our secondary endpoints. Factors … critically ill patients may be anticipated at the bedside
using predictor variables. Male patients with apparently normal or increased renal function …
using predictor variables. Male patients with apparently normal or increased renal function …
Antibiotic therapy in sepsis: No next time for a second chance!
B Shahrami, M Sharif… - Journal of Clinical …, 2021 - search.ebscohost.com
… Each hour delay in the administration of appropriate broad- spectrum antibiotics … in critically
ill patients with AKI compared to those with normal renal function or end- stage renal disease …
ill patients with AKI compared to those with normal renal function or end- stage renal disease …
Risk of acute kidney injury in combat-injured patients associated with concomitant vancomycin and extended-spectrum β-lactam antibiotic use
JM Yabes, L Stewart, F Shaikh… - Journal of intensive …, 2021 - journals.sagepub.com
… employ broad-spectrum antimicrobials; however, antibiotic … comprised of critically ill,
combat-related trauma patients, we … evaluated the persistence of renal dysfunction. Duration of …
combat-related trauma patients, we … evaluated the persistence of renal dysfunction. Duration of …
[PDF][PDF] … Infections in Critically Ill Patients—ESGCIP. Use of Antimicrobials for Bloodstream Infections in the Intensive Care Unit, a Clinically Oriented Review. Antibiotics …
… Secondary infections are especially common in patients with … reduce the exposure to
broad-spectrum antibiotics and prevent the … Conversely, renal or hepatic dysfunction may alter the …
broad-spectrum antibiotics and prevent the … Conversely, renal or hepatic dysfunction may alter the …
Prevention and management of antibiotic associated acute kidney injury in critically ill patients: new insights
I Karimzadeh, M Strader, SL Kane-Gill… - … in Critical Care, 2023 - journals.lww.com
… of kidney function, followed by a fixed maintenance dose of 60 mg q12h in patients with
impaired kidney function or … Cidofovir is a broad-spectrum antiviral that is primarily used for the …
impaired kidney function or … Cidofovir is a broad-spectrum antiviral that is primarily used for the …