Landscape of transcription termination in Arabidopsis revealed by single-molecule nascent RNA sequencing

W Mo, B Liu, H Zhang, X Jin, D Lu, Y Yu, Y Liu, J Jia… - Genome biology, 2021 - Springer
… , during which nascent RNA is released from the complex of RNA Polymerase II (Pol … The
kinetic competition between Pol II and exonuclease promotes termination [1, 2, 16]. As a result, …

Distinct transcription kinetics of pluripotent cell states

R Shao, B Kumar, K Lidschreiber… - Molecular Systems …, 2022 - embopress.org
RNA Pol II traverse encounters termination roadblocks imposed by DNA sequence or antisense
transcription … encounter stochastically determines if the polymerase comes to a complete …

Compatibility of termination mechanisms in bacterial transcription with inference on eukaryotic models

E Song, S Han, S Hohng, C Kang - Biochemical Society …, 2024 - portlandpress.com
… can occur at the first terminator, but if it fails, Sen1-dependent … cessation of transcription by
RNA polymerase II in the mouse … depends on kinetic coupling between RNA polymerase and …

[PDF][PDF] Sen1 is recruited to replication forks via Ctf4 and Mrc1 and promotes genome stability

R Appanah, EC Lones, U Aiello, D Libri, G De Piccoli - Cell reports, 2020 - cell.com
DNA replication and RNA transcription compete for the same … with nascent RNA exiting
from a stalled RNA polymerase II (… arise during DNA replication, we analyzed the kinetics of …

The nucleosome DNA entry-exit site is important for transcription termination in Saccharomyces cerevisiae

AE Hildreth, MA Ellison, AM Francette, JM Seraly… - bioRxiv, 2020 - biorxiv.org
… facilitate termination by serving as a barrier to RNA polymerase II progression and highlight
the importance of the DNA … Through kinetic competition with elongating Pol II (23), Sen1, a …

A crucial RNA-binding lysine residue in the Nab3 RRM domain undergoes SET1 and SET3-responsive methylation

KY Lee, A Chopra, GL Burke, Z Chen… - Nucleic Acids …, 2020 - academic.oup.com
… -K363R is associated with transcription termination defects in vivo and reduced RNA binding
affinity in vitro… Unravelling the means to an end: RNA polymerase II transcription termination

The nucleosome DNA entry-exit site is important for transcription termination and prevention of pervasive transcription

AE Hildreth, MA Ellison, AM Francette, JM Seraly… - elife, 2020 - elifesciences.org
… activity on RNA polymerase II termination suggest widespread kinetic competition. …
determinants of Nrd1-Nab3-Sen1-dependent transcription termination. The EMBO Journal 31:3935–…

Regulation of RNA polymerase II transcription by Spt4 in Saccharomyces cerevisiae

Ü Uzun - 2020 - ora.ox.ac.uk
termination, transcription of small non-coding RNAs including snRNAs and snoRNAs, are
terminated by the Nrd1, Nab3 and Sen1 dependent … a kinetic race between transcribing

The Mechanism of Transcription Termination by the PJW/PP1 Complex in Trypanosomatids

Y Zhang - 2023 - search.proquest.com
transcribed polycistronically by RNA polymerase II (RNAPII). Little is known about transcription
termination … RNAPII kinetics There is a kinetic competition between RNAP II and the 5’ to 3…

Real-time single-cell characterization of the eukaryotic transcription cycle reveals correlations between RNA initiation, elongation, and cleavage

J Liu, D Hansen, E Eck, YJ Kim, M Turner… - PLOS Computational …, 2021 - journals.plos.org
… into, for example, intrinsic transcriptional noise in yeast [23], kinetic splicing effects in
human … A slow RNA polymerase II affects alternative splicing in vivo. Molecular Cell. 2003;12(2):525…