Kinins and kinin receptors in cardiovascular and renal diseases

JP Girolami, N Bouby, C Richer-Giudicelli… - Pharmaceuticals, 2021 - mdpi.com
… –kinin system in arteries, heart and kidney and the consequences of kallikrein and kinin
actions in diseases … B1 or B2 receptor agonists and antagonists in cardiovascular diseases. …

Role of kinins in hypertension and heart failure

S Hamid, IA Rhaleb, KM Kassem, NE Rhaleb - Pharmaceuticals, 2020 - mdpi.com
… , or when endogenous kinin degradation is inhibited, kinins participate in the regulation of
… on cardiac diseases. Local cardiac KKS is believed to exert a significant cardiac protective …

Kinin B1 receptor: A target for neuroinflammation in hypertension

S Sriramula - Pharmacological Research, 2020 - Elsevier
… involvement of kinins in neuroinflammation and the development of cardiovascular diseases.
In particular, we will review relevant evidence regarding the role of kinin receptor mediated …

Kinin-kallikrein system: New perspectives in heart failure

K Mohammadi, D Shafie, N Ghomashi… - Heart Failure …, 2024 - Springer
… , kinins originate from kininogens through the action of tissue and plasma kallikreins. Some
impacts of kinins … vascular permeability may offer new treatments for cardiovascular diseases. …

Associations between plasma kinin B1 receptor levels and the presence and severity of coronary artery disease

Y Kishimoto, M Aoyama, E Saita, Y Ikegami… - … of Atherosclerosis and …, 2021 - jstage.jst.go.jp
… KB1R levels in patients with coronary artery disease (CAD). … , thus suggesting that kinin‑mediated
inflammation … levels in patients with coronary artery disease (CAD) have not …

Role of the renin–angiotensin–aldosterone and kinin–kallikrein systems in the cardiovascular complications of COVID-19 and long COVID

SL Cooper, E Boyle, SR Jefferson, CRA Heslop… - International Journal of …, 2021 - mdpi.com
… Populations most at risk of hospitalisation have been found to be the elderly and those
suffering from comorbidities such as cardiovascular disease and hypertension [5,6]. In many …

Kinins and their receptors in infectious diseases

APA Dagnino, MM Campos, RBM Silva - Pharmaceuticals, 2020 - mdpi.com
diseases. The present review article aims to discuss the role of the kinin system in infectious
diseases… Literature data provides compelling evidence about the participation of kinins in …

Kinins and their receptors as potential therapeutic targets in retinal pathologies

R Othman, G Cagnone, JS Joyal, E Vaucher… - Cells, 2021 - mdpi.com
… , and kinin receptors) are overexpressed in human and animal models of retinal diseases,
and … In this review, we provide an overview of the KKS with emphasis on kinin receptors in the …

Kinins and nitric oxide in patients with chronic chagas disease and systemic arterial hypertension

R Dellalibera-Joviliano, RB Bestetti, GS Lopes… - Cardiovascular …, 2020 - Elsevier
… , kinins are rapidly inhibited by kinase I (produced in blood) and II (surface of endothelial cells
and homologous to ECA) [14, [16], [17], [18]]. In addition, kinins … levels of kinins and NO in …

Novel anti-thrombotic mechanisms mediated by Mas receptor as result of balanced activities between the kallikrein/kinin and the renin-angiotensin systems

C Fang, AH Schmaier - Pharmacological Research, 2020 - Elsevier
… system and the kallikrein/kinin system, two overlapping plasma … prekallikrein in the
kallikrein/kinin system on endothelial cells … between the kallikrein/kinin and renin-angiotensin …