Prophylactic cefazolin concentrations in lumbar spine surgery: a comparison of tissue and plasma cefazolin concentrations to body composition
TB Pett - 2023 - researchspace.auckland.ac.nz
… weight-based system for cefazolin dosing, recommending a … Most guidelines recommend
intra-operative re-dosing after 2 … for re-dosing, and in fact sometimes do not use cefazolin half-…
intra-operative re-dosing after 2 … for re-dosing, and in fact sometimes do not use cefazolin half-…
Population pharmacokinetic model of cefazolin in total hip arthroplasty
J Lanoiselée, R Chaux, S Hodin, S Bourayou… - Scientific reports, 2021 - nature.com
… a population analysis of cefazolin pharmacokinetics (PK) and assess whether cefazolin
administration should be … Is tranexamic acid exposure related to blood loss in hip arthroplasty? A …
administration should be … Is tranexamic acid exposure related to blood loss in hip arthroplasty? A …
Perioperative administration of cefazolin and metronidazole in obese and non-obese patients: a pharmacokinetic study in plasma and interstitial fluid
C Dorn, D Petroff, M Stoelzel, MG Kees… - Journal of …, 2021 - academic.oup.com
… The in vivo relative recovery by loss was corrected for residual tissue … re-dosing of
cefazolin’ (after 2 h), as concluded from dosing … dosing is more important than timing of re-dosing. …
cefazolin’ (after 2 h), as concluded from dosing … dosing is more important than timing of re-dosing. …
Cefazolin prophylaxis in spine surgery: patients are frequently underdosed and at increased risk for infection
BA Karamian, GR Toci, MJ Lambrechts, N Siegel… - The Spine Journal, 2022 - Elsevier
… weight-based dose of preoperative cefazolin had an increased risk of infection following spinal
fusion surgery. Two grams prophylactic cefazolin … weight-based cefazolin dose; we were …
fusion surgery. Two grams prophylactic cefazolin … weight-based cefazolin dose; we were …
Dosage of presurgical cefazolin in obese and non-obese patients. Does weight matter?
B Rodriguez de Castro, MM Barbosa… - Revista Espanola de …, 2020 - europepmc.org
… prophylactic dose of two grams of cefazolin between obese and non-obese patients. … a
standard prophylactic dose of two grams of cefazolin between obese and non-obese patients. …
standard prophylactic dose of two grams of cefazolin between obese and non-obese patients. …
Antibiotic prophylaxis in bariatric surgical procedures: is there an ideal antimicrobial agent?
ÁAB Ferraz, F Santa-Cruz, CE Edmiston Jr - Surgical Infections, 2020 - liebertpub.com
… in intra-operative subtherapeutic concentrations of cefazolin … patients with obesity, and
weight-based dosing could be an … that include pharmacokinetic analysis of intra-operative tissue …
weight-based dosing could be an … that include pharmacokinetic analysis of intra-operative tissue …
[PDF][PDF] Individualized surgical antibiotic prophylaxis–why, when, and how?
… Lack of Pharmacokinetic Basis of Weight-Based Dosing and Intra-Operative Re-Dosing
with Cefazolin Surgical Prophylaxis in Obese Patients: Implications for Antibiotic Stewardship. …
with Cefazolin Surgical Prophylaxis in Obese Patients: Implications for Antibiotic Stewardship. …
[PDF][PDF] National surgical antibiotic prophylaxis guideline in Singapore
WTG Chung, H Shafi, J Seah, P Purnima… - Ann Acad Med …, 2022 - annals.edu.sg
… dosed if surgery is prolonged or there is significant blood loss… As vancomycin is less effective
than cefazolin in preventing SSI … The recommended re-dosing intervals for commonly used …
than cefazolin in preventing SSI … The recommended re-dosing intervals for commonly used …
[HTML][HTML] Antibiotics in anesthesia and critical care
A Premachandra, P Moine - Annals of Translational Medicine, 2024 - ncbi.nlm.nih.gov
… o Re-dosing should be based on the half-life of the antibiotic [… : for cefazolin 3.0 g if >120
kg; for aminoglycosides, dosing is … Because intra-operative contamination may occur at any …
kg; for aminoglycosides, dosing is … Because intra-operative contamination may occur at any …
Comparison of 2g vs 1 g of Prophylactic Cefazolin in Surgical Site Infections in Trauma Surgery Below the Knee
FRK Sanders, RMG Kistemaker… - Foot & Ankle …, 2020 - journals.sagepub.com
… pharmacokinetic and clinical results of prophylactic cefazolin … effect of a single dose of 2 g
compared with 1 g of cefazolin … , tourniquet use, estimated blood loss, fixation material, use …
compared with 1 g of cefazolin … , tourniquet use, estimated blood loss, fixation material, use …