… photodynamic therapy (aPDT) is a promising therapy to … (ROS), that leads to cytotoxicity
after light irradiation. Photoactive … and photobinding and photocleavage of DNA through a Ru(II…

… approach called photodynamic therapy (PDT), and we … (tpy)(NN)(L)] 2+ have been published
with different cytotoxic … PI value in vitro and the light-activated antitumor activity in vivo is, …

… Photodynamic therapy (PDT) is favored by π expansion and the … Some Ru(II) complexes
are known to bind to DNA upon … The cytotoxic species in ruthenium-based photoactivated …

… (PCT) and photodynamic therapy (PDT) behavior. Quantum … was shown to be critical for
achieving efficient, light-activated … responsible for the cytotoxicity of these compounds and is …

… of dark toxicity and DNA mutation. Herein, we reported a new … a series of NIR light-activated
Ru complexes using well-… The cytotoxicity of Ru-I toward MCF-7 cells was studied by …

… [Ru(dppz)(phen) 2 ]Cl 2 binds to DNA by intercalation. Therefore, we used [Ru(dppz) 2 phen]Cl
2 as a model for DNA … The (photo)cytotoxic effect against different cancer cells at different …

… with proteins and DNA to induce cell death. As photodynamic therapeutic agents, these
complexes have been widely … can absorb longer wavelength light and have less cytotoxic effect. …

… that the DNA aggregating properties of the compounds may be … in the cytotoxicity exhibited
by cyclometalated ruthenium … of action of compounds used in photodynamic therapy involves …

… One example is photodynamic therapy (PDT), an FDA-… oxygen species (ROS), importantly
cytotoxic singlet oxygen ( 1 O 2 )… -100), which are not light-activated, have advanced to clinical …

… cancer to induce cytotoxic activity by generating DNA damages. … ; for example, generation
of DNA double strand breaks and … compounds bearing an Ru–C bond, but not in compounds …