[HTML][HTML] Taking phototherapeutics from concept to clinical launch
BM Vickerman, EM Zywot, TK Tarrant… - Nature Reviews …, 2021 - nature.com
… Light-triggered BODIPY uncaging has been demonstrated to release several compounds. It
… The utility of the heptamethine cyanine scaffold as a near-infrared photocaging group was …
… The utility of the heptamethine cyanine scaffold as a near-infrared photocaging group was …
Turning Red without Feeling Embarrassed─ Xanthenium-Based Photocages for Red-Light-Activated Phototherapeutics
A Egyed, K Németh, TÁ Molnár, M Kállay… - Journal of the …, 2023 - ACS Publications
… In their continuing study, they have explored the yellow-light-triggered C–C bond
cleavage reactions of a pyronine derivative, (41) with a recent report describing its complex …
cleavage reactions of a pyronine derivative, (41) with a recent report describing its complex …
Conditionally activatable visible-light photocages
M Bojtár, K Németh, F Domahidy, G Knorr… - Journal of the …, 2020 - ACS Publications
… , thus, we hypothesized that similarly to fluorescence, the photoresponsivity of photocages
can also be modulated by the bioorthogonal and quencher tetrazine moiety. We have recently …
can also be modulated by the bioorthogonal and quencher tetrazine moiety. We have recently …
Photolytical reactions for light induced biological effectors release: on the road to the phototherapeutic window
… Photolabile precursors of biological effectors, also called caged compounds or photocaged
… also very attractive for drug release and light controlled drug release has been achieved with …
… also very attractive for drug release and light controlled drug release has been achieved with …
Near-infrared photocontrolled therapeutic release via upconversion nanocomposites
… (A) NIR photocontrolled doxorubicin delivery through photocaged mesoporous silica coated
… light triggered release of DOX. Reprinted with permission [53]. Copyright 2015, Wiley-VCH. …
… light triggered release of DOX. Reprinted with permission [53]. Copyright 2015, Wiley-VCH. …
[HTML][HTML] Photocage-selective capture and light-controlled release of target proteins
R Rakauskaitė, G Urbanavičiūtė, M Simanavičius… - Iscience, 2020 - cell.com
… to produce proteins with photocaged cysteine or selenocysteine … Employing the produced
photocage-selective binder, we … transfer and light-triggered removal of photo-caging groups. …
photocage-selective binder, we … transfer and light-triggered removal of photo-caging groups. …
Blue or Near-Infrared Light-Triggered Release of Halogens via Blebbistatin Photocage
Z Situ, W Chen, S Yang, X Fan, F Liu… - The Journal of …, 2022 - ACS Publications
… , we hypothesize that Bleb derivatives may be used as a photocage platform to release
different … (45) Therefore, in this work, we synthesized a series of Bleb derivatives with different …
different … (45) Therefore, in this work, we synthesized a series of Bleb derivatives with different …
Radical caging strategy for cholinergic optopharmacology
R Nakamura, T Yamazaki, Y Kondo… - Journal of the …, 2023 - ACS Publications
… Using this radical caging strategy to cage previously uncageable bioactive molecules,
we have photocaged molecules with no general labeling sites, including acetylcholine, an …
we have photocaged molecules with no general labeling sites, including acetylcholine, an …
[HTML][HTML] Photoremovable Protecting Groups
P Dunkel - Encyclopedia, 2022 - mdpi.com
… Besides a more efficient communication and collaboration between distinct scientific fields,
application-driven photocage development could also contribute in the future to the transition …
application-driven photocage development could also contribute in the future to the transition …
Photoactivatable o-Hydroxycinnamic Platforms for Bioimaging and Therapeutic Release: Miniperspective
… an alcohol release (eg, ethanol) on photoirradiation (Table 1, entry 1). Photocaged alcohol
1 … (b) Light-triggered drug release from MTPDDS (10 μM) in HeLa cells by photoirradiation at …
1 … (b) Light-triggered drug release from MTPDDS (10 μM) in HeLa cells by photoirradiation at …