… of the rationale for developing radiolabeled sdAbs for RPT … the ratio of internalized fraction
over surface bound fraction, … which has incorporated several distinguishing design features: a …

… This article describes radiolabeling, surface plasmon resonance, … Technical improvements
(near-total internal reflection … ability to sequence and identify large surface-bound proteins. …

… , or help to identify off-target tissues at risk for increased TP … antibody/fragment as an IgG
isotype/class-matched internal … However, for the sake of brevity we will limit our discussion of …

… target complexes undergo cellular internalization and degradation … Target receptor (brown
structure) exists in surface-bound and … First of all, despite a 25- to 50-fold difference in receptor …

… cell surface bound EVs prior to imaging the cells. At 37 C, PKH26-labeled EVs internalized
into cells … methodology remains relevant to evaluate any potential EV biocorona differences. …

… of the adaptive immune system to recognize and neutralize … (169) After surface-bound
antibodies capture C1q, a cascade … to the internalization and elimination of antibodies should also …

… recover the surface-bound [ 89 Zr]Zr-DFO-2Rs15d, cells were … The BT474 cells were
used to determine the internalization of [ … 2Rs15d can potentially be used to identify HER2-positive …

… 4 h, cell culture supernatants were removed, surface-bound activity was stripped from the …
to 5F7, which does internalize extensively. While this difference may be a factor influencing …

… FAPα, which is a cell surface-bound type II transmembrane … analysis, except a slight difference
between the uptake values of … with no internalization that limits their function for efficient …

… removed by washing cells and surface bound NCs were … and we would observe no difference
between NCs targeted to … transferrin was simultaneously internalized into the cells, thus …