Advances with antibody-drug conjugates in breast cancer treatment
MA Subhan, VP Torchilin - European Journal of Pharmaceutics and …, 2021 - Elsevier
… paratopic antibody displays better cellular internalization and … Following the administration
of unlabeled and radio-labeled … ADCs identify tumor antigen through binding with antibody. (2…
of unlabeled and radio-labeled … ADCs identify tumor antigen through binding with antibody. (2…
Integration of in vitro and in vivo models to predict cellular and tissue dosimetry of nanomaterials using physiologically based pharmacokinetic modeling
… was not discussed in the literature; however, we assume the differences in blood … % NPs
were internalized with the rest of the NPs interacting with cells remaining surface-bound. Uptake …
were internalized with the rest of the NPs interacting with cells remaining surface-bound. Uptake …
[HTML][HTML] Engineering mesoporous silica nanoparticles for drug delivery: where are we after two decades?
… , but a separate section below will be devoted to this aspect. … produce oligomeric/polymeric
surface-bound species. The example … of the silica and the internal and external surface of the …
surface-bound species. The example … of the silica and the internal and external surface of the …
[HTML][HTML] Recent progress in lipid nanoparticles for cancer theranostics: opportunity and challenges
SI Bukhari, SS Imam, MZ Ahmad, PR Vuddanda… - Pharmaceutics, 2021 - mdpi.com
… evaluating its extent to identify if it is … surface-bound nanomaterial, or it can be lodged in
bilayer lipids lamellae in liposomes, and certainly, the inorganic material can also be internalized …
bilayer lipids lamellae in liposomes, and certainly, the inorganic material can also be internalized …
[HTML][HTML] Current approaches of nanomedicines in the market and various stage of clinical translation
X Shan, X Gong, J Li, J Wen, Y Li, Z Zhang - Acta Pharmaceutica Sinica B, 2022 - Elsevier
… which are formulated with surface-bound polyethylene glycol (… , penetration and cell
internalization when delivered to the … can accurately distinguish normal cells from pathological …
internalization when delivered to the … can accurately distinguish normal cells from pathological …
[PDF][PDF] Cell-specific cargo delivery using synthetic bacterial spores
M Kong, D D'Atri, MT Bilotta, B Johnson, TB Updegrove… - Cell reports, 2023 - cell.com
… d Target cells internalize SSHELs; acidic pH in lysosomes liberates the cargo … At the
highest magnification, we could discern an individual SKBR3 cell with multiple surface-bound …
highest magnification, we could discern an individual SKBR3 cell with multiple surface-bound …
Nanoparticles in radiopharmaceutical sciences: Review of the fundamentals, characterization techniques and future challenges
S Huclier-Markai, C Alliot… - Journal of Materials …, 2020 - pubs.thesciencein.org
… They combine the advantages of multiplexed analytical tools in … We describe here mostly
post-radiolabeling processes, … particles, and differences in cellular internalization have been …
post-radiolabeling processes, … particles, and differences in cellular internalization have been …
Recent developments in aptasensors for diagnostic applications
… on the size difference between breast cancer cells and blood cells. … , the CD63 on the
exosome surface bound to the aptamers, … Andrade’s group also explored the use of radiolabeled …
exosome surface bound to the aptamers, … Andrade’s group also explored the use of radiolabeled …
Multiplexed analysis of the cellular uptake of polymeric nanocarriers
… Radiolabeling approaches suffer from stringent safety … cell samples, an Ir solution was again
added as an internal … the uptake of each NG in separate cell cultures (ie, uniplexed analysis) …
added as an internal … the uptake of each NG in separate cell cultures (ie, uniplexed analysis) …
[HTML][HTML] Hybrid chelator-based PSMA radiopharmaceuticals: Translational approach
H Lahnif, T Grus, S Pektor, L Greifenstein… - Molecules, 2021 - mdpi.com
… both the surface-bound and internalized radioactivity in … , as well as the application of
radiolabeled PSMA inhibitors, have … ] which could be due to differences in study design and setup. …
radiolabeled PSMA inhibitors, have … ] which could be due to differences in study design and setup. …