[HTML][HTML] Advances in protein-protein interaction network analysis for Parkinson's disease
JE Tomkins, C Manzoni - Neurobiology of Disease, 2021 - Elsevier
… PPI network with the ORFs located in different linkage disequilibrium … of high-quality proteomics
and genomics data opens the … (linked to disease risk) and changes in protein expression …
and genomics data opens the … (linked to disease risk) and changes in protein expression …
Revealing protein-protein interactions at the transcriptome scale by sequencing
… by our understanding of the interaction networks formed by the … proteome-scale map of the
human protein-protein interaction … translated protein from this mRNA is then covalently linked …
human protein-protein interaction … translated protein from this mRNA is then covalently linked …
Stitching the synapse: Cross-linking mass spectrometry into resolving synaptic protein interactions
MA Gonzalez-Lozano, F Koopmans, PF Sullivan… - Science …, 2020 - science.org
… In terms of PPIs, we generated an XL-based protein interaction network … Comparing our
cross-linking data with the accumulated … abundances were obtained from our previous proteomic …
cross-linking data with the accumulated … abundances were obtained from our previous proteomic …
[HTML][HTML] Comparison of path-based centrality measures in protein-protein interaction networks revealed proteins with phenotypic relevance during adaptation to …
M Gilbert, Z Li, XN Wu, L Rohr, S Gombos, K Harter… - … of proteomics, 2021 - Elsevier
… Individual interactions within the reconstructed network were … in protein-protein interaction
networks based on their network … to nodes that connect different network communities. In this …
networks based on their network … to nodes that connect different network communities. In this …
An atlas of protein-protein interactions across mouse tissues
MA Skinnider, NE Scott, A Prudova, CH Kerr… - Cell, 2021 - cell.com
… organization of proteins in networks of physical interactions. Mapping … However, the dynamics
of protein interactions across … efforts to profile the transcriptome, proteome, and epigenome …
of protein interactions across … efforts to profile the transcriptome, proteome, and epigenome …
Mass spectrometry‐based protein–protein interaction networks for the study of human diseases
AL Richards, M Eckhardt, NJ Krogan - Molecular systems biology, 2021 - embopress.org
… combined with quantitative MS, allow the proteome‐level analysis of complex biological
systems. … , linking KRAS activity to a myriad of adaptive network alterations spanning from core …
systems. … , linking KRAS activity to a myriad of adaptive network alterations spanning from core …
A novel insight into neurological disorders through HDAC6 protein–protein interactions
N Bahram Sangani, J Koetsier, J Mélius, M Kutmon… - Scientific Reports, 2024 - nature.com
… of our HDAC6 network, we mapped transcriptomics data of … here as a bridge that links
polyubiquitinated proteins (via its BUZ … Mapping the transcriptomics and proteomics data from drug …
polyubiquitinated proteins (via its BUZ … Mapping the transcriptomics and proteomics data from drug …
Heterogeneous multi-layered network model for omics data integration and analysis
… as protein-protein interaction, … network model needs more than three layers to connect
genome to phenome via epigenome (DNA layer), transcriptome (RNA layer), proteome (protein …
genome to phenome via epigenome (DNA layer), transcriptome (RNA layer), proteome (protein …
Proteomic and interactomic insights into the molecular basis of cell functional diversity
I Bludau, R Aebersold - Nature Reviews Molecular Cell Biology, 2020 - nature.com
… cell at the levels of the transcriptome, proteome and interactome (… and stable protein–protein
interactions (PPIs) and protein … , including cross-linking the full proteome of Escherichia coli, …
interactions (PPIs) and protein … , including cross-linking the full proteome of Escherichia coli, …
Combined transcriptome and proteome profiling of the pancreatic β-cell response to palmitate unveils key pathways of β-cell lipotoxicity
… networks were inferred in the RNA-seq and proteomics data separately using a random forest
algorithm to score predictors and then the 2 networks … identified in proteomics and black …
algorithm to score predictors and then the 2 networks … identified in proteomics and black …