GLUT4 dispersal at the plasma membrane of adipocytes: a super-resolved journey

A Geiser, S Foylan, PW Tinning, NJ Bryant… - Bioscience …, 2023 - portlandpress.com
… In adipose tissue, insulin stimulates glucose uptake by … hub between GLUT4 exocytosis and
re-internalisation. By … , suggested to be regulated by lipid rafts, the actin cytoskeleton, as well …

[HTML][HTML] Understanding the distinct subcellular trafficking of CD36 and GLUT4 during the development of myocardial insulin resistance

JJFP Luiken, M Nabben, D Neumann… - Biochimica et Biophysica …, 2020 - Elsevier
… In addition, localization of CD36 to lipid rafts and binding to … The fact two VAMPs are needed
for GLUT4 internalization, is … the GLUT4 endocytosis regulation by VAMP8 in adipose tissue

Dynamics of the plasma membrane transporter GLUT4

S Morris - 2020 - theses.gla.ac.uk
Adipose tissue is in fact significant for insulin sensitivity, as … Consequently, these cell types
require a glucose transport … the half-time for internalisation of labelled surface GLUT4, the …

Neuregulin 4 downregulation induces insulin resistance in 3T3-L1 adipocytes through inflammation and autophagic degradation of GLUT4 vesicles

F Díaz-Sáez, C Blanco-Sinfreu… - International Journal of …, 2021 - mdpi.com
… mostly expressed in brown adipose tissue (BAT) and white adipose tissue (WAT), … required
to maintain Glut4 content in 3T3-L1 adipocytes, since its downregulation leads to higher Glut4

Regulation of GLUT4 translocation in adipocytes: the role of SNARE proteins and caveolae

H Taylor - 2023 - stax.strath.ac.uk
… by a study that found that TC10, which is required for GLUT4 … by near absence of adipose
tissue, severe problems with lipidrequired for insulin stimulated GLUT4 translocation to the …

Lipid rafts as potential mechanistic targets underlying the pleiotropic actions of polyphenols

R Wang, W Zhu, J Peng, K Li, C Li - Critical Reviews in Food …, 2021 - Taylor & Francis
… extremely complex mix of lipids and proteins, necessary for normal cell functioning. … GLUT4
internalization in the absence of insulin (Yuan et al. Citation2007). A higher degree of GLUT4

LRP1-mediated AggLDL endocytosis promotes cholesteryl ester accumulation and impairs insulin response in HL-1 cells

V Actis Dato, A Benitez-Amaro, D de Gonzalo-Calvo… - Cells, 2020 - mdpi.com
cells also express GLUT1, which internalizes glucose in an insulin-independent manner [31].
Herein, we found that the GLUT4… to lipid rafts/caveolae domain. Likely, further studies are …

The spatial dynamics of insulin-regulated GLUT4 dispersal

AM Koester - 2021 - theses.gla.ac.uk
… affects intracellular GLUT4 trafficking pathways as well … membrane in adipocytes. Moreover,
we found a negative correlation between adipocyte cell area and insulin-stimulated GLUT4

EFR3 and phosphatidylinositol 4-kinase IIIα regulate insulin-stimulated glucose transport and GLUT4 dispersal in 3T3-L1 adipocytes

AM Koester, A Geiser, KME Laidlaw, S Morris… - Bioscience …, 2022 - portlandpress.com
… , GLUT4 is retained in clusters at the site of fusion; these clusters nucleate clathrin assembly
and are thought to represent sites of GLUT4 internalization. … PI4K-IIIα are required for insulin-…

Regulation of the Actin Cytoskeleton by Palmitate: Implications for Lymphatic Endothelial Barrier Function and Skeletal Muscle GLUT4 Translocation

VL Tokarz - 2023 - search.proquest.com
… impairs sorting of internalized GLUT4 from the cell surface .......… modify upstream signals
required for GLUT4 translocation .......… white fat depots: subcutaneous adipose tissue and visceral …