More Than Androgens: Hormonal and Paracrine Signaling in Prostate Development and Homeostasis
J Felgueiras, V Camilo, M Fardilha… - Tissue-Specific Cell …, 2020 - Springer
… of the prostatic acid phosphatase (ACPP) from rat prostate … ) of Bcl2-associated agonist
of cell death (BAD) [136]. … demonstrated in a castration-resistant PCa cell line in which in …
of cell death (BAD) [136]. … demonstrated in a castration-resistant PCa cell line in which in …
Cancer cell–extrinsic roles for the androgen receptor in prostate cancer
AW Hahn, BA Siddiqui, J Leo, E Dondossola… - …, 2023 - academic.oup.com
… of androgens via surgical castration or chemical castration with … for AR signaling, androgen
deprivation therapy (ADT, the … phenotype, including epithelial cell apoptosis, suggesting both …
deprivation therapy (ADT, the … phenotype, including epithelial cell apoptosis, suggesting both …
Modelling the distinct roles of epithelial and stromal androgen receptor in the regulation of prostate epithelial dynamics
IL Woodman - The FEBS Journal, 2023 - Wiley Online Library
… [6], indicating that castration-induced luminal cell death is not … of luminal cell apoptosis at
various timepoints after castration, … lobe-specific responses of the brown Norway rat prostate to …
various timepoints after castration, … lobe-specific responses of the brown Norway rat prostate to …
Androgens, aging, and prostate health
K Welén, JE Damber - Reviews in Endocrine and Metabolic Disorders, 2022 - Springer
… deprivation therapy (ADT), was proven 80 years ago, it has been the mainstay for the … in
castrated rats supplemented with increasing doses of androgens, that showed rapid prostate …
castrated rats supplemented with increasing doses of androgens, that showed rapid prostate …
[HTML][HTML] Mucinous metaplasia in Pten conditional knockout mice and mucin family genes as prognostic markers for prostate cancer
NJ Santos, PP Ximenes, FB Constantino, HF Carvalho… - Life sciences, 2022 - Elsevier
… was associated with castration-resistant prostate cancer (CRPC) … , thereby demonstrating
resistance to cell death. There is … to androgen deprivation therapy. This characteristic of …
resistance to cell death. There is … to androgen deprivation therapy. This characteristic of …
Preclinical and clinical research models of prostate cancer: a brief overview
D Basak, L Gregori, F Johora, S Deb - Life, 2022 - mdpi.com
… stimulating proliferation and suppressing apoptosis. Thus, … succumb to metastatic
castration-resistant prostate cancer (CRPC). … In TRAMP mice, the rat prostate governs the …
castration-resistant prostate cancer (CRPC). … In TRAMP mice, the rat prostate governs the …
AR loss in prostate cancer stroma mediated by NF-κB and p38-MAPK signaling disrupts stromal morphogen production
… Androgen deprivation therapy (ADT), which is the standard … leading to basal cell death and
their loss during oncogenesis. … Androgen regulation of the rat keratinocyte growth factor (KGF/…
their loss during oncogenesis. … Androgen regulation of the rat keratinocyte growth factor (KGF/…
[HTML][HTML] Lipogenic effects of androgen signaling in normal and malignant prostate
… in rodents were lobe-specific; testosterone induced m-… Castration of the rat or monkey results
in repression of lipogenic … inhibited PCa cell proliferation and activated cell death in LNCaP …
in repression of lipogenic … inhibited PCa cell proliferation and activated cell death in LNCaP …
Common biological factors implicated in benign prostatic hyperplasia and prostate cancer, conventional and phytotherapeutic approaches employed in management …
GC Pender, JH Ombaka, PG Mwitari, B Guyah - International Journal of …, 2024 - ijsra.net
… in both human [33] and rat prostate [34]. In another study, … Apoptosis is a physiological
regulatory mechanism which involves a series of molecular events culminating in cell death…
regulatory mechanism which involves a series of molecular events culminating in cell death…
[PDF][PDF] Targeting CBP/p300 and its downstream transcriptional machinery in advanced PCa
MD Adam Sharp, L Butler - e-century.us
… hormone-sensitive adenocarcinoma to NEPC after castration, … we assessed cell cycle
regulation, cell death related activities … of prostatic androgen receptor shows lobe-specific changes …
regulation, cell death related activities … of prostatic androgen receptor shows lobe-specific changes …