Cardiac regeneration after myocardial infarction: an approachable goal

M Giacca - Current cardiology reports, 2020 - Springer
… old piglets, while invariably leads to scarring in adult animals [17]. … the cardiac muscle can
be achieved by either the implantation of … Cardiomyocyte cell cycle activation improves cardiac

Cardiac cell therapy for heart repair: should the cells be left out?

D Zhu, K Cheng - Cells, 2021 - mdpi.com
… in infarcted myocardium with iPSC-CMs implantation, the … factor that drives cardiovascular
progenitor cell specification. … Restoring miR-21-5p expression rescued FEXO’s reparative …

Pericardial Grafting of Cardiac Progenitor Cells in Self-Assembling Peptide Scaffold Improves Cardiac Function After Myocardial Infarction

M Kanda, T Nagai, N Kondo, K Matsuura… - Cell …, 2023 - journals.sagepub.com
… The lengths of the scar and non-infarcted muscle were measured for both the endocardial
… and hydrophobic amino acid residues that could adopt β-sheet structures and form a stable …

Acellular bioscaffolds redirect cardiac fibroblasts and promote functional tissue repair in rodents and humans with myocardial injury

DA Svystonyuk, HEM Mewhort, AF Hassanabad… - Scientific Reports, 2020 - nature.com
… of infarcted myocardium, reduced myocardial scar burden, … microenvironments can instruct
the fate that fibroblasts adopt … and progenitor cells in conjunction with cardiac fibroblasts in …

Research progress on cardiac tissue construction of mesenchymal stem cells for myocardial infarction

GD Yang, DS Ma, CY Ma, Y Bai - Current Stem Cell Research & …, 2024 - ingentaconnect.com
… a scar tissue and eventually the heart going into heart failure. … that the nuclear DNA of the
rescued clones was unaltered, … that implanted MSCs reach the damaged myocardial tissue …

Pluripotent stem cell-derived mesenchymal stromal cells improve cardiac function and vascularity after myocardial infarction

S Thavapalachandran, TYL Le, S Romanazzo… - Cytotherapy, 2021 - Elsevier
… or significant impact on infarct scar size. Suggesting safety, … progenitor cells and to rescue
apoptotic cells after MI [36] … myoblast implants then set a precedent that endocardial stem cell

Cardiac fibroblasts and myocardial regeneration

W Chen, W Bian, Y Zhou, J Zhang - Frontiers in bioengineering and …, 2021 - frontiersin.org
… -pluripotent stem cells and induced cardiac progenitor cells, both … for replacing the myocardial
scar with active contractile tissue … also been observed in patients after implantation of a left-…

Regulation of endothelial progenitor cell functions in ischemic heart disease: new therapeutic targets for cardiac remodeling and repair

H Huang, W Huang - Frontiers in Cardiovascular Medicine, 2022 - frontiersin.org
… , which lead to fibrotic scarring during the replacement of lost … overexpression was found
to rescue EPC migratory and … and enhanced the repair of the infarcted myocardium (149). …

The potential properties of natural compounds in cardiac stem cell activation: their role in myocardial regeneration

C Carresi, M Scicchitano, F Scarano, R Macri, F Bosco… - Nutrients, 2021 - mdpi.com
… or cardiac progenitor cells (CPCs) when inoculated into the … are able to replenish the damaged
heart tissue (scar size) … the implanted stem cells [230]. The ability of resveratrol to improve …

Mesenchymal stem cells in cardiac repair: effects on myocytes, vasculature, and fibroblasts

SJ White, JJH Chong - Clinical therapeutics, 2020 - Elsevier
… The use of adult stem/progenitor cell therapy for myocardial … remuscularization of infarcted
myocardium in numerous large … stem cell–derived MSCs were shown to activate regulatory T …