A conserved subcomplex within the bacterial cytokinetic ring activates cell wall synthesis by the FtsW-FtsI synthase
LS Marmont, TG Bernhardt - Proceedings of the National …, 2020 - National Acad Sciences
… These polymers associate with membrane-anchored … FtsQLB complex that normally requires
additional input from or … , we believe that it faithfully represents the final step of septal PG …
additional input from or … , we believe that it faithfully represents the final step of septal PG …
An updated model of the divisome: regulation of the septal peptidoglycan synthesis machinery by the divisome
M Attaibi, T den Blaauwen - International journal of molecular sciences, 2022 - mdpi.com
… FtsW and the transpeptidase FtsI (also known as PBP3) [15]. … FtsW recruits FtsI, and both
are required for the midcell … of FtsI can localize to midcell independently of its periplasmic …
are required for the midcell … of FtsI can localize to midcell independently of its periplasmic …
Insights into the assembly and regulation of the bacterial divisome
TA Cameron, W Margolin - Nature Reviews Microbiology, 2024 - nature.com
… ring’ 1 , which is required for the localization of all the other divisome proteins. These FtsZ
polymers move directionally around the inner membrane by … FtsW and FtsI are essential septal …
polymers move directionally around the inner membrane by … FtsW and FtsI are essential septal …
Insights into the structure, function, and dynamics of the bacterial cytokinetic FtsZ-ring
R McQuillen, J Xiao - Annual Review of Biophysics, 2020 - annualreviews.org
… ’ location patterns do not exactly follow that of the Z-ring in … destabilized Z-ring, but the late
division proteins FtsK and FtsI … , rather than its localization pattern, is required for a symmetric, …
division proteins FtsK and FtsI … , rather than its localization pattern, is required for a symmetric, …
Conformational changes in the essential E. coli septal cell wall synthesis complex suggest an activation mechanism
… of FtsI supported by interactions between the membrane-distal … Little change was observed
in midcell localization of FtsI … be required for maintaining the active conformation of FtsI. …
in midcell localization of FtsI … be required for maintaining the active conformation of FtsI. …
Regulation of cytokinesis: FtsZ and its accessory proteins
M Wang, C Fang, B Ma, X Luo, Z Hou - Current genetics, 2020 - Springer
… , including FtsZ localization, Z-ring formation and stabilization, … FtsI is a penicillin-binding
protein (PBP3) with monofunctional transpeptidase activity. In E. coli, FtsI is required for septal …
protein (PBP3) with monofunctional transpeptidase activity. In E. coli, FtsI is required for septal …
Cell Division
R Gupta, N Gupta, R Gupta, N Gupta… - Fundamentals of Bacterial …, 2021 - Springer
… ) in order to anchor Z-ring to the cell membrane. The core domain … On the other hand, ftsI
mutant, gene encoding PBP3, … FtsW is followed by PBP3 which requires FtsW to localize, and …
mutant, gene encoding PBP3, … FtsW is followed by PBP3 which requires FtsW to localize, and …
Class A PBPs: It is time to rethink traditional paradigms
D Straume, KW Piechowiak, M Kjos… - Molecular …, 2021 - Wiley Online Library
… FtsE 4 FtsE FtsE FtsE ATPase required for the transmission … The PASTA domain is required
for midcell localization of StkP … The essential bPBPs, PBP2, and PBP3, are closely associated …
for midcell localization of StkP … The essential bPBPs, PBP2, and PBP3, are closely associated …
Early midcell localization of Escherichia coli PBP4 supports the function of peptidoglycan amidases
… First, FtsZ and its membrane bound partners ZipA and FtsA … sensitive alleles of FtsE, FtsQ
and PBP3 (FtsI) were grown in … the septal localization of PBP4 and that this requires FtsE. …
and PBP3 (FtsI) were grown in … the septal localization of PBP4 and that this requires FtsE. …
Cell division protein FtsZ: from structure and mechanism to antibiotic target
N Silber, CL Matos de Opitz, C Mayer… - Future microbiology, 2020 - Taylor & Francis
… the midcell localization of FtsZ and the formation of the Z-ring (in … that contribute to Z-ring
dynamics and membrane tethering. Late… of the TXA709 oral dose required for efficacy. Since the …
dynamics and membrane tethering. Late… of the TXA709 oral dose required for efficacy. Since the …