[HTML][HTML] Long-term follow-up of full-thickness skin grafting in giant incisional hernia repair: a randomised controlled trial
V Holmdahl, B Stark, L Clay, U Gunnarsson, K Strigård - Hernia, 2022 - Springer
V Holmdahl, B Stark, L Clay, U Gunnarsson, K Strigård
Hernia, 2022•SpringerPurpose Conventional repair of a giant incisional hernia often requires implantation of a
synthetic mesh (SM). However, this surgical procedure can lead to discomfort, pain, and
potentially serious complications. Full-thickness skin grafting (FTSG) could offer an
alternative to SM, less prone to complications related to implantation of a foreign body in the
abdominal wall. The aim of this study was to compare the use of FTSG to conventional SM in
the repair of giant incisional hernia. Methods Patients with a giant incisional hernia (> 10 cm …
synthetic mesh (SM). However, this surgical procedure can lead to discomfort, pain, and
potentially serious complications. Full-thickness skin grafting (FTSG) could offer an
alternative to SM, less prone to complications related to implantation of a foreign body in the
abdominal wall. The aim of this study was to compare the use of FTSG to conventional SM in
the repair of giant incisional hernia. Methods Patients with a giant incisional hernia (> 10 cm …
Purpose
Conventional repair of a giant incisional hernia often requires implantation of a synthetic mesh (SM). However, this surgical procedure can lead to discomfort, pain, and potentially serious complications. Full-thickness skin grafting (FTSG) could offer an alternative to SM, less prone to complications related to implantation of a foreign body in the abdominal wall. The aim of this study was to compare the use of FTSG to conventional SM in the repair of giant incisional hernia.
Methods
Patients with a giant incisional hernia (> 10 cm width) were randomised to repair with either FTSG or SM. 3-month and 1-year follow-ups have already been reported. A clinical follow-up was performed 3 years after repair, assessing potential complications and recurrence. SF-36, EQ-5D and VHPQ questionnaires were answered at 3 years and an average of 9 years (long-term follow-up) after surgery to assess the impact of the intervention on quality-of-life (QoL).
Results
Fifty-two patients were included. Five recurrences in the FTSG group and three in the SM group were noted at the clinical follow-up 3 years after surgery, but the difference was not significant (p = 0.313). No new procedure-related complication had occurred since the one-year follow-up. There were no relevant differences in QoL between the groups. However, there were significant improvemnts in both physical, emotional, and mental domains of the SF-36 questionnaire in both groups.
Conclusion
The results of this long-term follow-up together with the results from previous follow-ups indicate that autologous FTSG as reinforcement in giant incisional hernia repair is an alternative to conventional repair with SM.
Trial Registration
The study was registered August 10, 2011 at ClinicalTrials.gov (ID NCT01413412), retrospectively registered.
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