… indicated that purinergic signaling elements were potential targets for … long-term cardiac
transplant survival in murine cardiac transplantation models (128). Blocking P2X7 receptors …

… central to the viability and long-term success of allografts. Here … in cardiac-transplanted
humans and mice and that P2X7 … treatment in vasculopathy in heart transplantation, and another …

… Purinergic receptors have been targeted for the treatment of … enough to activate P2X7, P2Y
2 , and P2Y 6 receptors, which … play a role in long-term potentiation and synaptic plasticity […

… , being seven PX2 ionotropic nucleotide receptors that act on … P2Y nucleotides related to the
long-term cellular activity (trophic) … target, as mentioned several times in this review, is P2X7, …

… Purinergic P2X7 receptor, a nonselective cation channel, is … targeting P2X7 receptor may
protect against cardiac … by activated fibroblasts under the long-term stimulation of IL-18 and IL-…

… These purinergic receptors can be subdivided into the ionotropic (… After long-term treatment,
muscle strength recovered to … Thus, P2X7 is an attractive therapeutic target with at least one …

… long-term command, adenosine and ATP promote cell pro… of the P2X7 receptor leads
to the tonic and pro-survival effect. … act as a pharmacological target for cancer therapy [101]. …

… a family of purinergic receptors. … a long-term treatment, muscle strength recovered to almost
wild type levels [32•]. These data identify P2X7 purinoceptor blockade as an attractive target …

… Hypertension is the leading cause of morbidity and mortality … of ionotropic glutamate receptors
and P2 receptors caused a … The mechanisms underlying the relation between P2X7 gene …

… receptors (with four subtypes), P2X ionotropic nucleotide … Long-term control by ATP and
adenosine of cell proliferation and … pain P2X4, P2X7, and P2Y 12 receptors on microglia have …