Purinergic Signaling in Parkinson's Disease
… agonism attenuated hyperkinetic movement in long-term … In conclusion, P1 receptors could
be considered as targets for … our understanding of P2X7 receptor physiological functions. …
be considered as targets for … our understanding of P2X7 receptor physiological functions. …
Purinergic signaling during Marek's disease in chickens
… (PRs) have been reported as potential therapeutic targets for … In the current study, the
higher expression of P2X7 in MDV-… has been reported to improve recurrence-free survival in …
higher expression of P2X7 in MDV-… has been reported to improve recurrence-free survival in …
Microglial activation modulated by P2X4R in ischemia and repercussions in Alzheimer's disease
C Castillo, F Saez-Orellana, PA Godoy… - Frontiers in …, 2022 - frontiersin.org
… The upregulation and increased activity of purinergic receptors activated by ADP/ATP,
specially P2X4R, which has a high permeability to calcium and is mainly expressed in microglial …
specially P2X4R, which has a high permeability to calcium and is mainly expressed in microglial …
[HTML][HTML] … , Immunity, Fibrosis, and Infection: Synapomorphic features of hepatic and pulmonary vasculatures include comparable purinergic signaling responses in host …
D Hanidziar, SC Robson - American Journal of Physiology …, 2021 - ncbi.nlm.nih.gov
… In contrast, P2X7 receptor targeting was also found to produce … reduction in liver injury and
improved survival of mice with sepsis (… vascular remodeling and tissue fibrosis over long-term. …
improved survival of mice with sepsis (… vascular remodeling and tissue fibrosis over long-term. …
[PDF][PDF] In vitro produced neuronal network studies on the role of P2X7 receptor and its relevance to alzheimer's disease
L Francistiová - 2022 - phd.mater.uni-mate.hu
… From amongst both ionotropic (P2X) and metabotropic (P2Y) … - Establishment and long term
maintenance of hiPSC-… , suggesting this receptor as a potential therapeutic target for acute …
maintenance of hiPSC-… , suggesting this receptor as a potential therapeutic target for acute …
Crosstalk between the purinergic and immune systems: Implications for the glutathione antioxidant system in health and disease
CE Assmann, N Stefanello, NB Bottari… - … and Oxidative Stress …, 2020 - books.google.com
… binding to activated integrins on the target cells [52]. Alkaline … [104] showed an increase in
the P2X7 purinergic receptor in … [113] showed that ATP could mediate the long-term effects of …
the P2X7 purinergic receptor in … [113] showed that ATP could mediate the long-term effects of …
Synapomorphic features of hepatic and pulmonary vasculatures include comparable purinergic signaling responses in host defense and modulation of inflammation
D Hanidziar, SC Robson - American Journal of Physiology …, 2021 - journals.physiology.org
… In contrast, P2X7 receptor targeting was also found to produce … reduction in liver injury and
improved survival of mice with sepsis (… vascular remodeling and tissue fibrosis over long-term. …
improved survival of mice with sepsis (… vascular remodeling and tissue fibrosis over long-term. …
Role and therapeutic targets of P2X7 receptors in neurodegenerative diseases
H Zheng, Q Liu, S Zhou, H Luo, W Zhang - Frontiers in Immunology, 2024 - frontiersin.org
… ALS is a long-term neurological disorder defined by the invasion of lesions, mainly in the …
In an animal model of AD, BBG reduced levels of purinergic receptors, decreased gliosis, and …
In an animal model of AD, BBG reduced levels of purinergic receptors, decreased gliosis, and …
Trained immunity—basic concepts and contributions to immunopathology
J Ochando, WJM Mulder, JC Madsen… - Nature Reviews …, 2023 - nature.com
… Interestingly, P2X7 blockade abrogated the T helper 1 (T H 1… T cells, and promoted long-term
transplant survival in mice 99 . … in rejection in a vascularized heart transplant model in mice …
transplant survival in mice 99 . … in rejection in a vascularized heart transplant model in mice …
Differential effects of heat-inactivated, secretome-deficient MSC and metabolically active MSC in sepsis and allogenic heart transplantation
ARR Weiss, O Lee, E Eggenhofer, E Geissler… - Stem Cells, 2020 - academic.oup.com
… It further indicates that viable MSC target different host immune cell populations than …
Survival time of allografts in a fully allogenic heart transplant model. C57BL/6 mice served …
Survival time of allografts in a fully allogenic heart transplant model. C57BL/6 mice served …