… damage and mortality in sepsis. Consequently, interventions targeting chemotaxis hold …
Panx1-mediated purinergic signals activate P2X 2 receptors, leading to IL-33 production in …

… CRACs), purinergic P2 receptors, and transient receptor potential (… Long-term and systematic
studies emphasized the … develop specific drugs targeting the exciting P2X7/TRPC channel, …

… ATP is the endogenous ligand of purinergic ionotropic (P2X) … BCI used in the subsequent
long-term experiments (≥24 h). … their survival; and 3) pharmacological interventions targeting …

… Among purinergic receptors, the ionotropic ATP-gated P2X7 … Moreover, an antagonist of this
receptor showed a long-term … suggesting that targeting the P2X7 receptor may have disease-…

… levels of A2A and P2X7 receptors in neurological … purinergic receptors is further classified
into two different families, (1) P2X receptors, are ionotropic ligand-gated ion channel receptors …

… signals to target cells by binding to purine receptors that can … also express other purinergic
receptors, including P2X7, P2Y6… prognostic factor for long-term survival in patients with GC. …

… potassium through the purinergic receptor P2X7 after activation … target for CVD has led to
the study of several targeted IL-1 … improves longterm outcomes in humans with heart failure of …

… Current knowledge of ATP as it relates to targeted receptor(s… However, we have performed
long-term HLMC culture (2 … In any case, these reports suggest that P2X4R, but not P2X7, …

… along with low toxicity during long-term use are needed. In … of an ionotropic purinergic receptor
P2X7 increased ENaC … pharmaceuticals to target PANX and/or and PANX/P2X7 complex. …