Stress affects central compensation of neural responses to cochlear synaptopathy in a cGMP-dependent way
D Savitska, M Hess, D Calis, P Marchetta… - Frontiers in …, 2022 - frontiersin.org
… A loss of afferent auditory fibers (cochlear synaptopathy) can … However, threshold sensitivity
in response to pure-tone … nerve response (ABR wave I), and inner hair cell ribbons, which we …
in response to pure-tone … nerve response (ABR wave I), and inner hair cell ribbons, which we …
Detecting noise-induced cochlear synaptopathy by auditory brainstem response in tinnitus patients with normal hearing thresholds: A meta-analysis
… of synapses between the inner hair cells (IHCs) and auditory … , questioning the sensitivity
of wave I amplitude to detect CS. … central enhancement to compensate for reduced neural …
of wave I amplitude to detect CS. … central enhancement to compensate for reduced neural …
Current topics in hearing research: Deafferentation and threshold independent hearing loss
M Trevino, E Lobarinas - Hearing research, 2022 - Elsevier
… as a result of synaptopathy and/or inner hair cell loss. … inner hair cell damage, including loss
of afferent synapses, … understanding of auditory system plasticity and compensation. Results …
of afferent synapses, … understanding of auditory system plasticity and compensation. Results …
Contrasting mechanisms for hidden hearing loss: Synaptopathy vs myelin defects
… Studies on animal models suggest two possible pathogenic mechanisms for HHL: (1)
loss of synapses between inner hair cells and auditory nerve fibers, and (2) disruption of …
loss of synapses between inner hair cells and auditory nerve fibers, and (2) disruption of …
Inner hair cell synapse density influences auditory processing
… proposed that inner hair cell (IHC) synaptopathy, ie, loss of … reflecting homeostatic
compensation in the auditory brainstem … Loss of auditory sensitivity from inner hair cell …
compensation in the auditory brainstem … Loss of auditory sensitivity from inner hair cell …
Auditory-nerve responses in mice with noise-induced cochlear synaptopathy
K Suthakar, MC Liberman - Journal of neurophysiology, 2021 - journals.physiology.org
… the increased sensitivity to rapid temporal-envelope modulations can be attributed … lack of
hair cell damage in the present study strongly suggests that improved temporal precision can …
hair cell damage in the present study strongly suggests that improved temporal precision can …
Loss of Pex1 in Inner Ear Hair Cells Contributes to Cochlear Synaptopathy and Hearing Loss
… To determine if compensation occurs in the VGlut3 Cre/Cre … Pex1 fl/fl mice compensate
centrally for the reduced cochlear … , would predict high sensitivity to noise induced hearing loss …
centrally for the reduced cochlear … , would predict high sensitivity to noise induced hearing loss …
[HTML][HTML] Disturbed balance of inhibitory signaling links hearing loss and cognition
… responses as a stress-sensitive process. Ultimately, under … , spontaneous glutamate release
from inner hair cells (IHCs), … centrally compensate age-dependent cochlear synaptopathy…
from inner hair cells (IHCs), … centrally compensate age-dependent cochlear synaptopathy…
[PDF][PDF] Deciphering compromised speech-in-noise intelligibility in older listeners: the influence of cochlear synaptopathy
M Garrett, V Vasilkov, M Mauermann, JL Wilson… - bioRxiv, 2020 - scholar.archive.org
… role of synaptopathy and hearing sensitivity for speech … ent synapses between hair cells
and auditory-nerve bers … compensate for the functional consequences of synaptopathy. …
and auditory-nerve bers … compensate for the functional consequences of synaptopathy. …
Age-dependent auditory processing deficits after cochlear synaptopathy depend on auditory nerve latency and the ability of the brain to recruit LTP/BDNF
P Marchetta, D Savitska, A Kübler, G Asola, M Manthey… - Brain Sciences, 2020 - mdpi.com
… of auditory nerve fibers from hair cells (cochlear synaptopathy… that cochlear synaptopathy,
if centrally compensated through … who have maintained good hearing sensitivity, nevertheless …
if centrally compensated through … who have maintained good hearing sensitivity, nevertheless …