… drive the loss of maturational arrest via activation of NF-κB pathway [… NF-κB activation leads
to increased expression of known targets, such as COX-2 and inducible nitric oxide synthase …

… nitric oxide release; and, importantly, reduced proteoglycan … and downregulating NF-κB
as well as the potential to induce a … due to hypomethylation at CpG sites which may be itself …

… Next, we discuss the timely updates concerning cell death … (SOD2) and inducible nitric
oxide synthase (iNOS)]. DNA … NF-κB pathway, as well as Mmp13 and Adamts5 expression, …

… the production of inducible nitric oxide synthase (iNOS), … NF-κB coordinates aberrant
cartilage catabolic pathways by … as lack of access to synovial tissues of patients and also lack …

… Loss of methylation in CpG sites in the NF-κB enhancer elements of inducible nitric oxide
synthase is responsible for gene induction in human articular chondrocytes. Arthr Rhuem. 2013…

… toward a net loss of cartilage [18]. The breakdown products of … -chain-enhancer of activated
B cells (NF-κB), phosphoinositide 3-… showed that methylation of the −110 bp CpG site, which …

… And then, chondrocytes were stained with In Situ Cell Death … inhibition of inducible nitric
oxide synthase is preferred as a … mTOR and NF-κB serve as master modulators responsible for …

… as TNF-α, IL-6, nitric oxide. There are two states of MG activation, … in CpG sites. Mammalian
genomes’ promoters show high … of NF-κB repressed NF-κB-dependent gene expression in …

… pathways like MAPK and 39 NF-κB during this process 158. … species (ROS), IL-1β, nitric
oxide (NO), Fas, 34 and tumor … with IL-1β leads to decreased 31 methylation at CpG sites in …

… Moreover, NF-κB may, in addition to promote an increased secretion of … The up-regulation
of TNF-α also impairs nitric oxide (NO) … of CpG sites in the promotor region of important genes …