… programmed to intravenously deliver 0.75 mg/kg of cocaine per … locomotor response to
cocaine and cumulative cocaine … : the high cocaine-responder and low cocaine-responder model …

… of variation in cocaine response and intravenous self-… locomotor differences predicted
initial locomotor response to … We assessed conditioned activation by comparing locomotor …

… to exposing them to cocaine using conditioned place preference (CPP… a lower locomotor
response to cocaine develop cocaine-… a lower locomotor response to intravenous cocaine have …

… preclinical research on traits that predict drug self-administration … , and (3) the conditioned
locomotor response to a cocaine-paired … All data were collected using the Med-PC IV software …

… stress response system and reactivity to novelty predict the … dark phase from the facial vein
in heparinized collection tubes … Cocaine-induced locomotion during the third conditioning trial …

… Next, we assessed rats’ acquisition of intravenous cocaine … did not differ in their locomotor
response to a novel environment … and initial cocaine reactivity, we measured locomotor activity …

… Both a lower dose of cocaine (10 mg/kg, ip, 7 days treatment) and a 7-day exposure to …
challenge injection of cocaine that was sufficient to drive a robust locomotor response (Figure 1E) …

… This behavior has been observed in male HR rats during cocaine self-administration,
with HRs consuming more drug when cost is low compared to LR rats (O’Connor et al. 2021). …

… conditioning paradigm to quantify the preference for cocaine … cocaine lever presses on
the cocaine dose–response stage … was strongly and significantly predicted by sensory lever …

… escalation behavior would reliably predict performance of other … We examined locomotor
sensitization in groups that … an attenuated initial locomotor response to cocaine, which could …