Self-administration acquisition latency predicts locomotor sensitivity to cocaine in male rats
S Rakela, BW Sortman, C Gobin, S Hao… - Behavioural Brain …, 2024 - Elsevier
… programmed to intravenously deliver 0.75 mg/kg of cocaine per … locomotor response to
cocaine and cumulative cocaine … : the high cocaine-responder and low cocaine-responder model …
cocaine and cumulative cocaine … : the high cocaine-responder and low cocaine-responder model …
Characterization of genetically complex Collaborative Cross mouse strains that model divergent locomotor activating and reinforcing properties of cocaine
… of variation in cocaine response and intravenous self-… locomotor differences predicted
initial locomotor response to … We assessed conditioned activation by comparing locomotor …
initial locomotor response to … We assessed conditioned activation by comparing locomotor …
Individual differences in dopamine uptake in the dorsomedial striatum prior to cocaine exposure predict motivation for cocaine in male rats
JK Shaw, I Pamela Alonso, SI Lewandowski… - …, 2021 - nature.com
… to exposing them to cocaine using conditioned place preference (CPP… a lower locomotor
response to cocaine develop cocaine-… a lower locomotor response to intravenous cocaine have …
response to cocaine develop cocaine-… a lower locomotor response to intravenous cocaine have …
Sensitivity to food and cocaine cues are independent traits in a large sample of heterogeneous stock rats
CP King, JA Tripi, AR Hughson, AP Horvath… - Scientific reports, 2021 - nature.com
… preclinical research on traits that predict drug self-administration … , and (3) the conditioned
locomotor response to a cocaine-paired … All data were collected using the Med-PC IV software …
locomotor response to a cocaine-paired … All data were collected using the Med-PC IV software …
Hyperfunction of the stress response system and novelty‐induced hyperactivity correlate with enhanced cocaine‐induced conditioned place preference in NCAM …
B Kähler, EV Romswinkel, M Jakovcevski… - Addiction …, 2021 - Wiley Online Library
… stress response system and reactivity to novelty predict the … dark phase from the facial vein
in heparinized collection tubes … Cocaine-induced locomotion during the third conditioning trial …
in heparinized collection tubes … Cocaine-induced locomotion during the third conditioning trial …
[HTML][HTML] Novelty preference does not predict trait cocaine behaviors in male rats
… Next, we assessed rats’ acquisition of intravenous cocaine … did not differ in their locomotor
response to a novel environment … and initial cocaine reactivity, we measured locomotor activity …
response to a novel environment … and initial cocaine reactivity, we measured locomotor activity …
[HTML][HTML] Cocaine shifts dopamine D2 receptor sensitivity to gate conditioned behaviors
… Both a lower dose of cocaine (10 mg/kg, ip, 7 days treatment) and a 7-day exposure to …
challenge injection of cocaine that was sufficient to drive a robust locomotor response (Figure 1E) …
challenge injection of cocaine that was sufficient to drive a robust locomotor response (Figure 1E) …
Novelty-induced locomotor behavior predicts heroin addiction vulnerability in male, but not female, rats
BN Kuhn, N Cannella, AD Crow, AT Roberts… - …, 2022 - Springer
… This behavior has been observed in male HR rats during cocaine self-administration,
with HRs consuming more drug when cost is low compared to LR rats (O’Connor et al. 2021). …
with HRs consuming more drug when cost is low compared to LR rats (O’Connor et al. 2021). …
Effects of isolation housing stress and mouse strain on intravenous cocaine self-administration, sensory stimulus self-administration, and reward preference
M Leonardo, S Brunty, J Huffman, DB Lester… - Scientific Reports, 2023 - nature.com
… conditioning paradigm to quantify the preference for cocaine … cocaine lever presses on
the cocaine dose–response stage … was strongly and significantly predicted by sensory lever …
the cocaine dose–response stage … was strongly and significantly predicted by sensory lever …
Intermittent but not continuous access to cocaine produces individual variability in addiction susceptibility in rats
AF Garcia, IG Webb, LM Yager, MB Seo… - …, 2020 - Springer
… escalation behavior would reliably predict performance of other … We examined locomotor
sensitization in groups that … an attenuated initial locomotor response to cocaine, which could …
sensitization in groups that … an attenuated initial locomotor response to cocaine, which could …