[HTML][HTML] Bidirectional association between physical activity and dopamine across adulthood—A systematic review

A Marques, P Marconcin, AO Werneck, G Ferrari… - Brain sciences, 2021 - mdpi.com
… individual’s vulnerability (ie, reducing anxiety and depressive … to determine dopamine D2/D3
receptor availability using ( 18 … an increase in striatal dopamine D2/D3 receptor availability …

[HTML][HTML] Regulation of voluntary physical activity behavior: a review of evidence involving dopaminergic pathways in the brain

A Ruiz-Tejada, J Neisewander, CS Katsanos - Brain Sciences, 2022 - mdpi.com
low D2 receptor density [40], and is also linked to increased … impaired dopaminergic activity
in obesity results in reduced … each experiment, such as early exposure to a running wheel. …

The impact of a high-fat diet on physical activity and dopamine neurochemistry in the striatum is sex and strain dependent in C57BL/6J and DBA/2J mice

MS Totten, CW Wallace, DM Pierce… - Nutritional …, 2022 - Taylor & Francis
… , such as reduced physical activity, dysregulated dopamine … In humans, obesity has
been associated with decreased fine … differences in susceptibility to developing obesity and …

[HTML][HTML] Impact of dopamine-related genetic variants on physical activity in old age–a cohort study

IM Dohrn, G Papenberg, E Winkler… - … and physical activity, 2020 - Springer
… interventions to increase physical activity and reduce sedentary … link to D2 receptor density.
The A1 allele has been related to a … Environmental exposure, such as being more physically

[HTML][HTML] High intensity interval training exercise increases dopamine D2 levels and modulates brain dopamine signaling

J Tyler, M Podaras, B Richardson, N Roeder… - Frontiers in Public …, 2023 - frontiersin.org
… efficacy of exercise in treating addiction due to its ability to reduce D1R-… motivation and
decreased D2 receptor signaling with … and exercise in which higher-intensity physical activity was …

[HTML][HTML] High intensity interval training exercise increases dopamine D2 levels and modulates brain dopamine signaling

J Tyler, M Podaras, B Richardson, N Roeder… - Frontiers in Public …, 2023 - frontiersin.org
… efficacy of exercise in treating addiction due to its ability to reduce D1R-… motivation and
decreased D2 receptor signaling with … and exercise in which higher-intensity physical activity was …

Obesity and dietary fat influence dopamine neurotransmission: Exploring the convergence of metabolic state, physiological stress, and inflammation on dopaminergic …

CW Wallace, SC Fordahl - Nutrition research reviews, 2022 - cambridge.org
… -induced obesity and HFD with reduced dopamine release … dopamine D1 receptor (D1R)
and dopamine D2 receptor (D2R) … with obesity susceptibility dependent on the activation of NAc …

Dopamine D2 receptor overexpression in the nucleus accumbens core induces robust weight loss during scheduled fasting selectively in female mice

AC Welch, J Zhang, J Lyu, MS McMurray… - Molecular …, 2021 - nature.com
reduces physical activity in lean mice, while restoring Gi signaling in iMSNs increases activity
in obese mice … DIO-susceptible rats show increased expression of the GTPase accelerating …

Striatal dopamine D2 receptors regulate cost sensitivity and behavioral thrift

D Mourra, F Gnazzo, S Cobos, JA Beeler - Neuroscience, 2020 - Elsevier
Using a homecage foraging paradigm with mice, we … increase appetitive motivation and
consumption, possibly contributing to reduced physical activity commonly observed in obesity. …

[HTML][HTML] Striatal dopamine D2-like receptors availability in obesity and its modulation by bariatric surgery: A systematic review and meta-analysis

G Ribeiro, A Maia, G Cotovio, FPM Oliveira… - Scientific Reports, 2023 - nature.com
… of dopamine receptors, with D1 and D2 receptors being … , associated with impaired physical
activity 52 . Another study … , the dynamic vulnerability model of obesity 66 proposes that an …