[HTML][HTML] The rise and fall of dopamine: a two-stage model of the development and entrenchment of anorexia nervosa

JA Beeler, NS Burghardt - Frontiers in psychiatry, 2022 - frontiersin.org
… when combined with high levels of physical activity. This … Impaired dopamine found in obese
individuals (108) may … , we expect vulnerable mice to show dopamine escalation followed …

Genetic variation of the dopamine D2 receptor gene: Association with the reinforcing value of food and eating in the absence of hunger in Chilean children

AM Obregón, V Vega, G Goldfield… - Nutricion …, 2020 - discovery.ucl.ac.uk
exposure to food (5), sweets (6), and sexual activity (7). … participants with obesity have fewer
dopamine D2 receptors (… basal metabolic rate by the appropriate physical activity factor. The …

The long-term interaction of diet and dopamine D2 gene expression on brain microglial activation

C Rapp, J Hamilton, K Blum, PK Thanos - Psychiatry Research …, 2022 - Elsevier
… suggest that decreased D2R levels may increase vulnerability to … in the D2 receptor are
prone to obesity through dramatic … that mice with reduced D2 expression show increased [ 3 H]…

[HTML][HTML] High-fat diet-induced weight gain, behavioral deficits, and dopamine changes in young C57BL/6J mice

J Han, P Nepal, A Odelade, FD Freely, DM Belton… - Frontiers in …, 2021 - frontiersin.org
… HFD and high sugar diet-induced obese rats (10). The C57BL… Dopamine D1 and D2
receptors in the hippocampus and … of dopaminergic molecules at the end of the dietary exposure

[HTML][HTML] Commentary on vulnerability and resilience to activity-based anorexia and the role of dopamine

JA Beeler, NS Burghardt - Journal of experimental neurology, 2021 - ncbi.nlm.nih.gov
… how caloric restriction and increased physical activity interact to … reducing wheel running
activity and progressively increasingincrease in light cycle running we observe in vulnerable

Nucleus accumbens D1-and D2-expressing neurons control the balance between feeding and activity-mediated energy expenditure

R Walle, A Petitbon, GR Fois, C Varin… - Nature …, 2024 - nature.com
… mice, we found that activity of dopamine D1 receptor-expressing … On the other hand, obesity
is associated with physical … of D2 receptor expression mainly result from physical activity-…

[HTML][HTML] Dopaminergic activity and exercise behavior in anorexia nervosa

S Gorrell, AGE Collins, D Le Grange, TT Yang - OBM neurobiology, 2020 - ncbi.nlm.nih.gov
… ambient heat may decrease physical activity in human AN (25)… of DA D2 receptor genes may
be a susceptibility factor in the … that decreasing DA does not reduce motivation to exercise in …

Nucleus accumbens D1 receptor–expressing spiny projection neurons control food motivation and obesity

BA Matikainen-Ankney, AA Legaria, Y Pan… - Biological …, 2023 - Elsevier
… that mice made obese with ad libitum exposure to a high fat … output of D1 SPNs or D2 SPNs
reduces and enhances lever-… the nonspecific nature of global dopamine receptor targeting. It …

Reduced phasic dopamine release and slowed dopamine uptake occur in the nucleus accumbens after a diet high in saturated but not unsaturated fat

CN Barnes, CW Wallace, BS Jacobowitz… - Nutritional …, 2022 - Taylor & Francis
… a decrease in post-synaptic D 2 receptor binding is associated with obesity, susceptibility
to … the ERK signaling pathway via PI3 K/Akt kinase signaling to regulate DAT activity [Citation46…

Therapeutic potential of dopamine agonists in the treatment of type 2 diabetes mellitus

MT Kabir, J Ferdous Mitu, R Akter, MF Akhtar… - … Science and Pollution …, 2022 - Springer
… cabergoline are also effective in reducing the glycemic level in … alcohol, gaining overweight,
and lack of physical activity can … D2 receptors is more elucidated than the other receptors like …